Topical Treatments for Melasma and Their Mechanism of Action

Topical Treatments for Melasma and Their Mechanism of Action - PMC

Evidence has shown ascorbic acid, azelaic acid, glycolic acid, kojic acid, salicylic acid, and niacinamide to be effective as adjuvant therapies with minimal ...

TC therapy continues to be the gold standard of care. Topical cysteamine and TA are newer options that can be incorporated as adjuvant and maintenance ...

New oral and topical approaches for the treatment of melasma

There has been much interest recently in the use of Polypodium leucotomos (PL) as an adjunct photoprotective agent in melasma. Polypodium is a fern of the ...

Different therapeutic approaches in melasma: advances and ...

Tranexamic acid can be administered through either oral, intradermal, or topical route for melasma treatment (Shankar et al., 2014; Adalatkhah and Sadeghi- ...

Medical therapies for melasma - Mahajan - 2022 - Wiley Online Library

Topical corticosteroids are rarely used alone for treating melasma due to their cutaneous adverse effects such as skin atrophy, facial ...

An Update on New and Existing Treatments for the Management of ...

In a randomised vehicle-controlled trial of 38 women, 68% rated their melasma as improved or much improved with 0.1% tretinoin compared with 5% ...

Topical Treatments for Melasma - Journal of Drugs in Dermatology

in categories according to their risk and benefit to patients with melasma. ... TABLE 3. Mechanism of Action of Topical Agents. Mechanism of Action. Drug.

Melasma Treatment & Management - Medscape Reference

The most commonly accepted treatment remains strict sun avoidance often in combination with a topical combination hydroquinine cream.

Topical Treatments for Melasma: A Systematic Review of ...

Conclusions: Cysteamine, triple combination therapy, and tranexamic acid received strong clinical recommendations for the treatment of melasma. Cysteamine has ...

TOPICAL TREATMENT OF MELASMA - Indian Journal of Dermatology

The mechanism of the skin-lightening effect of topical corticosteroids is ill-understood. Melanocytes respond to a wide variety of chemical mediators. The ...

An Updated Review of Melasma Treatments - Dermatology Advisor

Tranexamic Acid (TA): Topical and oral TA have demonstrated efficacy for the treatment of melasma in some studies, with clinical effect ...

Mechanism of Action of Topical Tranexamic Acid in the Treatment of ...

Tranexamic acid (TXA) has anti-plasmin activity and has been shown when administered orally to be effective against melasma, for which it is ...

Topical Treatments for Melasma: A Systematic Review of ...

Cysteamine, TC, and TXA received the strongest recommendation of benefit. These medications had greater efficacy and/or milder AE profiles compared with ...

Topical Treatments for Melasma and Their Mechanisms of Action.

Revised Date: 07/2011 Accessibility Information and Tips Deducing Multidecadal Anthropogenic Global Warming Trends Using Multiple Regression Analysis

A Review on Topical Management of Melasma

Hydroquinone (HQ), azelaic acid, kojic acid, glycolic acid, salicylic acid, and tretinoin are just a few of the many substances that have been utilized to ...

Topical Treatments for Melasma: A Systematic Review of ...

Conclusions: Cysteamine, triple combination therapy, and tranexamic acid received strong clinical recommendations for the treatment of melasma.

Tranexamic acid in melasma: A focused review on drug ...

We recommend that intralesional TXA be used as an adjuvant to topical medications in difficult-to-treat melasma. However, there are limited data ...

Update on Melasma—Part II: Treatment | Dermatology and Therapy

Clobetasol is a potent topical steroid that promotes rapid clearing of melasma pigmentation. The mechanism of depigmentation promoted by ...

Different administration routes of tranexamic acid in the treatment of ...

It can be administered orally, topically, via microinjection, or microneedle delivery. Although the mechanism of action of TA in the treatment of melasma has ...

Newer and upcoming therapies for melasma

The existing and most tried topical therapy is hydroquinone and the triple combination with tretinoin and corticosteroids, which is considered the gold standard ...