Toward a Functional Annotation of the Human Genome Using ...

Systematic approaches to achieve rapid and accurate functional annotation of a large number of uncharacterized genes are urgently needed in this postgenomic era ...

Toward a functional annotation of the human genome using artificial ...

Toward a functional annotation of the human genome using artificial transcription factors ... Genome Res. 2003 Dec;13(12):2708-16. doi: 10.1101/gr.1397903.

AWARD SUMMARY for Richard Myers, HAIB (U54HG006998)

TOWARD A COMPREHENSIVE FUNCTIONAL ANNOTATION OF THE HUMAN GENOME ... The goal of the ENCODE Project is to provide the biomedical community with a complete and ...

SNPnexus: a web server for functional annotation of human genome ...

The scope for data annotation has been substantially expanded to enhance biological interpretations of queried variants. This includes the ...

Toward Identification of Functional Sequences and Variants in ...

Understanding the noncoding part of the genome, which encodes gene regulation, is necessary to identify genetic mechanisms of disease and ...

Functional mapping and annotation of genetic associations with FUMA

Chromatin interaction mapping is used to map SNPs to genes when there is a significant chromatin interaction between the disease-associated ...

Emerging applications of read profiles towards the functional ...

Advances in HTS technology have opened several new avenues for the functional annotation of the genome using novel approaches. We have discussed about one ...

practical guide for the functional annotation of genetic variations ...

Abstract. Broader functional annotation of known as well as putative genetic variations is a valuable mean for prioritizing targets in ...

Genome annotation: From human genetics to ... - Cell Press

Second, current human annotations are biased toward tran- scripts ... annotate protein-coding function in human genes could serve as a ...

Genome annotation: From human genetics to biodiversity genomics

While the concept of the gene is controversial, genes can be operationally associated to transcriptional units, i.e., loci in the DNA sequence ...

Functional annotation of HOT regions in the human genome - Nature

Advances in genome-wide association studies (GWAS) and large-scale sequencing studies have resulted in an impressive and growing list of ...

A computational interactome and functional annotation for the ... - eLife

We show, using Gene Set Enrichment Analysis (GSEA), that predicted interaction partners can be used to annotate a protein's function. We provide ...

Functional Annotation of Proteome Encoded by Human ...

To enable identification of novel peptides and correction of existing gene annotations in the human genome, five alternative databases were used ...

Genome annotation: From human genetics to biodiversity genomics

This piece briefly reviews the basics of protein-coding gene prediction, discusses challenges in finalizing annotation of the human genome,

Genome-wide analysis of the transcription factor binding preference ...

We identified 1210 bi-directional gene pairs based on the GRCh37 assembly data, accounting for 11.6% of all the human genes owning RNAs. CpG ...

Functional annotation of genome : r/bioinformatics - Reddit

If you have your protein sequences in FASTA format you can look up functional annotation tools. KofamKOALA for example. It would help to ...

Functional annotation of HOT regions in the human genome - OUCI

AbstractAdvances in genome-wide association studies (GWAS) and large-scale sequencing studies have resulted in an impressive and growing list of disease- ...

An integrated and comparative approach towards identification ...

We provide an integrated and comparative in silico candidate gene identification, characterization and annotation approach, with an emphasis on ...

Abstract - GeneMark

Moreover finding the genes and deciphering gene structure is only the first step towards the automatic annotation of genomic sequences; attaching relevant ...

(PDF) FAVOR: functional annotation of variants online resource and ...

They provide an unprecedented resource for illuminating the genetic basis of human diseases. Variant functional annotations play a critical role ...