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Toward metabolome|based 13 C flux analysis


(13)C-based metabolic flux analysis - PubMed

Stable isotope, and in particular (13)C-based flux analysis, is the exclusive approach to experimentally quantify the integrated responses of metabolic ...

13C-based metabolic flux analysis | Nature Protocols

Stable isotope, and in particular 13C-based flux analysis, is the exclusive approach to experimentally quantify the integrated responses of ...

Toward metabolome-based 13 C flux analysis: a universal tool for ...

Metabolomics; Chapter. Toward metabolome-based 13C flux analysis: a universal tool for measuring in vivo metabolic activity. Chapter; First ...

A guide to 13 C metabolic flux analysis for the cancer biologist - Nature

... based analysis approach is required to extract flux information from the labeling data. In the past 20 years, 13C-MFA has emerged as the ...

13 C metabolic flux analysis: Classification and characterization ...

Based on the differences between the isotopic compositions of the metabolic precursor and the product, the relative fraction of metabolic fluxes converging to a ...

13C-Metabolic Flux Analysis: An Accurate Approach to Demystify ...

Such isotopic distributions, i.e., MDV, will then be used for the pathway and flux analysis [46]. Based on the MDV of various metabolites, the metabolic ...

13C Metabolic Flux Analysis - ScienceDirect.com

This minireview summarizes these recent developments and sketches the major practical problems. An outlook to possible future developments concludes the text.

Metabolic networks in motion: 13 C‐based flux analysis - EMBO Press

Blank LM, Kuepfer L, Sauer U (2005) Large‐scale 13C‐flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast.

13C Metabolic Flux Analysis - Institute of Molecular Systems Biology

Quantification of all fluxes is prohibitively difficult. Instead, other approaches such as RNAseq or metabolomics are proficiently used to formulate ...

Novel biological insights through metabolomics and 13C-flux analysis

We focus here on applications of metabolomics and flux methods to bacteria that address biological key questions in functional genomics, pathway identification ...

One‐shot 13C15N‐metabolic flux analysis for simultaneous ...

In contrast to the conventionally used single‐model approaches, BMA‐based 13C15N‐MFA enables not only the rigorous statistical inference of net ...

A Guide to 13C Metabolic Flux Analysis for the Cancer Biologist

Here Maciek Antoniewicz reviews 13C metabolic flux analysis (MFA) for quantifying intracellular fluxes in cancer cell metabolism.

OpenFLUX: efficient modelling software for 13C-based metabolic ...

We have developed a fast, accurate application to perform steady-state 13C metabolic flux analysis. OpenFLUX will strongly facilitate and ...

Toward metabolome-based 13C flux analysis: a universal tool for ...

In the first part of this chapter, the principles and issues of current 13C flux analysis methods are described, following the entire process from ...

Novel biological insights through metabolomics and 13C-flux analysis

Metabolic flux analysis based on 13 C-stable isotope labeling is one key technology to decipher in vivo reaction ratios and rates of a metabolic network and its ...

(13)C-based metabolic flux analysis. - Abstract - Europe PMC

Stable isotope, and in particular (13)C-based flux analysis, is the exclusive approach to experimentally quantify the integrated responses of metabolic ...

GC/MS-based 13C metabolic flux analysis resolves the parallel and ...

To date, the contribution of these pathways to photomixotrophic metabolism has remained unclear. Results. Here, we developed a comprehensive ...

13 C Metabolic Flux Analysis - SpringerLink

13 C MFA is an experimental approach to compute intracellular flux pattern. It involves tracer studies where substrates are labeled with stable isotopes, such ...

13C-MFA - Creative Proteomics

Creative Proteomics is a professional metabolomics company that leverages its metabolic flux analysis platform to meet the needs of our customers for ...

13 C-based metabolic flux analysis - Springer Nature Experiments

Stable isotope, and in particular 13C-based flux analysis, is the exclusive approach to experimentally quantify the integrated responses of metabolic ...