Trade|offs between gene expression

Trade-offs between gene expression, growth and phenotypic ...

Bacterial cells have a limited number of resources that can be allocated for gene expression. The intracellular competition for these resources has an ...

Trade-offs between gene expression, growth and phenotypic ...

Limitations in gene expression also play a role in generating phenotypic diversity, which is advantageous in fluctuating environments, at the expenses of ...

Mechanistic links between cellular trade-offs, gene expression, and ...

Our model couples gene expression with growth rate and growth rate with a growing population of cells. We show that the model recovers Monod's law for the ...

Central dogma rates and the trade-off between precision ... - Nature

cerevisiae indicate that expressing a non-beneficial mRNA penalizes the growth rate in proportion to the transcription rate (Methods). In E.

Limitations and Trade-offs in Gene Expression due to Competition ...

gene expression: an in silico investigation into the interactions between synthetic gene circuits and their chassis cell, arXiv:1309.7798, 2013. [14] D ...

Gene Expression Tradeoffs Determine Bacterial Survival and ...

Bacteria tend to overexpress stress response genes at the expense of reduced growth, conferring greater protection against further antibiotic exposure.

The fitness trade-off between growth and stress resistance ...

... gene expression signature whose expression levels are related to the fitness trade-off between growth preference and stress resistance ...

Gene expression tradeoffs determine bacterial survival and ...

To optimize their fitness, cells face the crucial task of efficiently responding to various stresses. This necessitates striking a balance ...

Limitations and trade-offs in gene expression due to competition for ...

In particular, we identify the limitations and trade-offs in gene expression by characterizing the attainable combinations of protein concentrations. We further ...

Shaping of microbial phenotypes by trade-offs - Nature

In many circumstances, there exist trade-offs between growth and other important traits (e.g., adaptability and survival) due to physiological ...

The cost of gene expression underlies a fitness trade-off in yeast

Here, we show that the cost of gene expression underlies a trade-off between growth rate and mating efficiency in the yeast Saccharomyces cerevisiae. During ...

Gene Expression Space Shapes the Bioprocess Trade-Offs among ...

Our goal is to fulfill industry-level overproduction demands optimally, as measured by the following key performance metrics: titer, productivity rate, and ...

Evolutionary trade-offs between baseline and plastic gene ...

The choice between these strategies is species specific and often involves evolutionary trade-offs between genetic variation and plasticity, ...

Tradeoffs and Optimality in the Evolution of Gene Regulation: Cell

Once this constraint is relieved by mutation, adaptation proceeds toward the optimum, yielding LacI with an altered allosteric mechanism that enables an ...

Mechanistic links between cellular trade-offs, gene expression ... - HAL

We develop a mechanistic cellular model built around these three trade-offs. The model predicts allocation of the proteome, energy turnover, and physiological ...

Trade-offs, Pleiotropy, and Shared Molecular Pathways: A Unified ...

The genetic and mechanistic underpinning of trade-offs can be found in the pleiotropic nodes that occur in the biological pathways shared ...

Trade‐offs between the instantaneous growth rate and long‐term ...

As a consequence, the expression of particular proteins is at the expense of others, causing trade-offs between cellular objectives such as ...

Allelic correlation is a marker of trade-offs between barriers to ...

One way in which such information processing is accomplished is via genetic networks in which the products of certain genes regulate the ...

(PDF) Trade-offs between gene expression, growth and phenotypic ...

Limitations in gene expression also play a role in generating phenotypic diversity, which is advantageous in fluctuating environments, at the ...

A life-history trade-off gene with antagonistic pleiotropic effects on ...

Traditionally, trade-offs are understood in terms of competition for limited resources among traits within an organism, which could be mediated ...