Transcription||replication conflicts

Transcription–replication conflicts: how they occur and how ... - Nature

Here we review recent data on the factors and mechanisms that are involved in either preventing or resolving transcription–replication collisions, and on their ...

Consequences and Resolution of Transcription–Replication Conflicts

Transcription–replication conflicts occur when the two critical cellular machineries responsible for gene expression and genome duplication collide with each ...

Transcription–Replication Conflicts as a Source of Genome Instability

Transcription and replication both require large macromolecular complexes to act on a DNA template, yet these machineries cannot ...

Transcription-Replication Conflicts as a Source of Genome Instability

Transcription and replication both require large macromolecular complexes to act on a DNA template, yet these machineries cannot ...

Direct visualization of transcription-replication conflicts reveals post ...

Transcription-replication collisions (TRCs) are crucial determinants of genome instability. R-loops were linked to head-on TRCs and proposed ...

Replication–Transcription Conflicts: A Perpetual War on the ...

DNA replication and transcription occur in all living cells across all domains of life. Both essential processes occur simultaneously on the ...

Excessive transcription-replication conflicts are a vulnerability of ...

In BRCA1 deficient cells, MEPCE depletion leads to R-loop accumulation, transcription stress, and transcription-replication conflicts, which ...

Transcription-Replication Conflicts: Orientation Matters - ScienceDirect

TRCs may occur in a head-on or co-directional fashion, depending on the orientation of genes relative to the direction of fork progression.