- Transmembrane peptides as unique tools to demonstrate the in vivo ...🔍
- Design and development of stapled transmembrane peptides that ...🔍
- Probing GPCR Dimerization Using Peptides🔍
- Transmembrane peptide effects on bacterial membrane integrity and ...🔍
- Advances in therapeutic peptides targeting G protein|coupled ...🔍
- Discovery and mechanistic characterization of a structurally|unique ...🔍
- Structural plasticity of a transmembrane peptide allows self ...🔍
- Cell|Penetrating Peptides🔍
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Angiotensin (ANGII) and secretin (SCT) share overlapping, interdependent osmoregulatory functions in brain, where SCT peptide/receptor function is required ...
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Several transmembrane (TM) peptides of these receptors were able to affect their conformation within complexes, reducing receptor BRET signals. AT1aR TM1 ...
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex · Figures · References · Related ...
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Fingerprint. Dive into the research topics of 'Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex' ...
Transmembrane peptides as unique tools to demonstrate the in vivo ...
Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex. 2014-03-04. 2014. Lee LT, Ng SY, Chu JY, Sekar ...
Design and development of stapled transmembrane peptides that ...
13. Lee, L.T.O. ∙ Ng, S.Y.L. ∙ Chu, J.Y.S. ... Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex.
Probing GPCR Dimerization Using Peptides - Frontiers
... Protein-Coupled Receptor ... Transmembrane Peptides as Unique Tools to Demonstrate the In Vivo Action of a Cross-Class GPCR Heterocomplex.
Transmembrane peptide effects on bacterial membrane integrity and ...
The overall results indicate that the designed TM peptides can be successfully targeted toward and inserted into the bacterial membrane to outcompete ...
Design and development of stapled transmembrane peptides that ...
In summary, our results provide proof of concept for using NanoBiT to study membrane protein complexes and for stabilizing disrupting peptides ...
Advances in therapeutic peptides targeting G protein-coupled ...
... demonstrate unique signalling profiles in vivo, but. whether this ... Impact story: developing the tools to evaluate complex drug products: ...
Discovery and mechanistic characterization of a structurally-unique ...
Membrane active peptides (MAPs) represent a class of short peptide (< 50 AAs), with cationic (+2 to +9) and amphipathic amino acids, that display excellent ...
Structural plasticity of a transmembrane peptide allows self ... - PNAS
We have found that properly modified synthetic analogs of transmembrane domains of membrane proteins can self-assemble into remarkably uniform spherical ...
Cell-Penetrating Peptides: Emerging Tools for mRNA Delivery - MDPI
CPPs, including cationic, amphipathic, and hydrophobic peptides, can be flexibly designed to possess various functions for biomedical ...
Membrane receptor activation mechanisms and transmembrane ...
Recently, studies using short peptides composed of the TMDs of receptors have provided unique insights into receptor function. TMD peptides have ...
De novo-designed transmembrane proteins bind and regulate a ...
Computational design has the potential to generate custom tool molecules directly targeting membrane proteins at their functional TM regions.
Transmembrane Peptides as a New Strategy to Inhibit ... - Frontiers
For TM2, TAT-IntPep and IntPep-RKR simulations, the central part of the peptides defined between P316 and S333 fits well with an α-helical ...
Peptides Evaluated In Silico, In Vitro, and In Vivo as Therapeutic ...
Bioactive peptides typically consist of 2–20 amino acids (aa) and represent unique protein fragments that exert several beneficial effects on physiological ...
Membrane receptor activation mechanisms and transmembrane ...
Here we explore recent evidence that, depending on the target receptor, TMD peptides can not only inhibit but also activate target receptors, ...
Mechanism and uses of a membrane peptide that targets tumors ...
The pH-selective insertion and folding of a membrane peptide, pHLIP [pH (low) insertion peptide], can be used to target acidic tissue in vivo, ...
Computational Design of Pore-Forming Peptides with Potent ...
(5,6) Similar to bacterial cell killing activity, pore-forming peptides exhibit direct cytotoxicity against cancer cells and therefore offer an ...