Tumor|Induced Local and Systemic Impact on Blood Vessel Function

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Here, we discuss how vascular function is altered in malignant tissue and distant organs in individuals with cancer and how leukocytes function as potent ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Endothelial dysfunction plays a role in several processes that contribute to cancer-associated mortality. The vessel wall serves as a barrier for metastatic ...

Tumor‐Induced Local and Systemic Impact on Blood Vessel Function

Vascular function is impaired both at local tumor level and systemic level in an individual with cancer. The primary tumor secretes ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Recent findings also suggest that leukocyte-mediated effects on vascular function are not limited to the primary tumor or tissues that represent metastatic ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function.

Recent findings also suggest that leukocyte-mediated effects on vascular function are not limited to the primary tumor or tissues that represent metastatic ...

The impact of VEGF on cancer metastasis and systemic disease

Because of these pathological features of tumor vessels, VEGF promotes tumor growth, invasion and metastasis. ... In addition to targeting local blood vessels in ...

Modulating cancer mechanopathology to restore vascular function ...

(B) Tumor stiffening and accumulation of intratumoral mechanical forces that are exerted on tumor blood vessels cause vessel compression and ...

Cancer metastasis through the lymphatic versus blood vessels

They can invade local lymphatic vessels and travel to regional lymph nodes or sentinel lymph nodes (SLNs), enter the bloodstream to reach ...

Angiogenic signaling pathways and anti-angiogenic therapy for cancer

Angiogenesis, the formation of new blood vessels, is a complex and dynamic process regulated by various pro- and anti-angiogenic molecules, ...

Coagulome and the tumor microenvironment: an actionable interplay

... blood and impacts both local and systemic aspects of cancer, including metastasis. ... 99. Martin, J.D. ... Normalizing function of tumor vessels ...

Altered function of blood vessels in tumor tissue and distant organs ...

Altered function of blood vessels in tumor tissue and distant organs in individuals with cancer. Vascular function is impaired both at local tumor level and ...

Neutrophil Extracellular Traps Accumulate in Peripheral Blood ...

Mice with tumors display impaired vascular function in peripheral tissue. Systemic vascular effects of cancer were analyzed using two well-established ...

Tumour vessel remodelling: new opportunities in cancer treatment in

Tumour blood vessel normalisation restores vascular function thereby increasing tumour perfusion and alleviating hypoxia. This in turn increases the ...

Defining the role of the tumor vasculature in antitumor immunity and ...

Cancer cells incite the formation of new blood and lymphatic vessels from preexisting vessels to cope with their high nutrient/oxygen demand and ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Tumor-Induced Local and Systemic Impact on Blood Vessel Function. J. Cedervall ； A. Dimberg ； A-K. Olsson. 《Mediators of Inflammation》 2015卷 (2015/12) Pp ...

Vasculitis: Symptoms, Types & Treatment - Cleveland Clinic

If you have vasculitis, your blood vessels swell and thicken. This makes it harder for blood to flow through them. Over time, the inflammation can damage your ...

The role of corticosteroids in the regulation of vascular tone

A similar result was obtained in dogs, where contractile responses were assessed by increases in systemic blood pressure, and norepinephrine and adrenal extract ...

Extracellular vesicles as central regulators of blood vessel function ...

The formation of metastasis of most solid tumors relies on blood vessels. Cancer cells in the primary tumor intravasate in tumor blood vessels ...

Effects of acid-base imbalance on vascular reactivity - SciELO

This suggests that non-enzymatically derived NO contributes to the "metabolic-acidic" local blood flow regulation in rat aorta (45). In systemic vessels, ...

Angiogenesis and Hepatocellular Carcinoma: From Molecular ...

However, it should be considered that newly formed tumor blood vessels having structural and functional defects may further aggravate hypoxia, thereby ...