Tumor‐Induced Local and Systemic Impact on Blood Vessel Function

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Here, we discuss how vascular function is altered in malignant tissue and distant organs in individuals with cancer and how leukocytes function as potent ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Endothelial dysfunction plays a role in several processes that contribute to cancer-associated mortality. The vessel wall serves as a barrier for metastatic ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Recent findings also suggest that leukocyte-mediated effects on vascular function are not limited to the primary tumor or tissues that represent metastatic ...

The impact of VEGF on cancer metastasis and systemic disease

Thus, the VEGF-induced cancer metastasis involves various steps of the sophisticated metastatic cascade. In addition to targeting local blood vessels in tumors, ...

Tumor-Induced Local and Systemic Impact on Blood Vessel Function.

Endothelial dysfunction plays a role in several processes that contribute to cancer-associated mortality. The vessel wall serves as a barrier for metastatic ...

Systemic Effects of Cancer Think Tank April 16 – 17, 2024

Thus, hormonal effects on the tumor microenvironment, both local and systemic, have significant impact in the progression of ... blood vessels to ...

Modulating cancer mechanopathology to restore vascular function ...

(B) Tumor stiffening and accumulation of intratumoral mechanical forces that are exerted on tumor blood vessels cause vessel compression and ...

Altered function of blood vessels in tumor tissue and distant organs ...

Altered function of blood vessels in tumor tissue and distant organs in individuals with cancer. Vascular function is impaired both at local tumor level and ...

Defining the role of the tumor vasculature in antitumor immunity and ...

Cancer cells incite the formation of new blood and lymphatic vessels from preexisting vessels to cope with their high nutrient/oxygen demand and ...

Extracellular vesicles as central regulators of blood vessel function ...

The formation of metastasis of most solid tumors relies on blood vessels. Cancer cells in the primary tumor intravasate in tumor blood vessels ...

Neutrophil Extracellular Traps Accumulate in Peripheral Blood ...

Mice with tumors display impaired vascular function in peripheral tissue. Systemic vascular effects of cancer were analyzed using two well-established ...

Cancer metastasis through the lymphatic versus blood vessels

They can invade local lymphatic vessels and travel to regional lymph nodes or sentinel lymph nodes (SLNs), enter the bloodstream to reach ...

Alterations in NO- and PGI2- dependent function in aorta in the ...

... systemic endothelial dysfunction induced by cancer ... “Tumor-Induced Local and Systemic Impact on Blood Vessel Function,” Mediat Inflamm.

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Tumor-Induced Local and Systemic Impact on Blood Vessel Function. J. Cedervall ； A. Dimberg ； A-K. Olsson. 《Mediators of Inflammation》 2015卷 (2015/12) Pp ...

The systemic-level repercussions of cancer-associated inflammation ...

Nonetheless, the tumor-associated inflammatory state not only has repercussions in its immediate local microenvironment, but the release of various components ...

The evolving tumor microenvironment: From cancer initiation to ...

Endothelial cells (ECs) form a single cell layer that lines all blood vessels. Tumor ECs display a remarkable heterogeneity and plasticity, and ...

The role of corticosteroids in the regulation of vascular tone

A similar result was obtained in dogs, where contractile responses were assessed by increases in systemic blood pressure, and norepinephrine and adrenal extract ...

Angiogenesis and Hepatocellular Carcinoma: From Molecular ...

However, it should be considered that newly formed tumor blood vessels having structural and functional defects may further aggravate hypoxia, thereby ...

Vasculitis: Symptoms, Types & Treatment - Cleveland Clinic

If you have vasculitis, your blood vessels swell and thicken. This makes it harder for blood to flow through them. Over time, the inflammation can damage your ...

Role of vascular normalization in benefit from metronomic ... - PNAS

In turn, malignant cell density could directly affect vascular function through compression of blood vessels. The function of tumor vessels can be improved by ...