Tumor Microenvironment Immune Response in Pancreatic Ductal ...

Neoadjuvant FOLFIRINOX with or without chemoradiation may induce immunologically relevant changes in the tumor microenvironment.

Whether neoadjuvant therapy-induced tumor immune response contributes to the improved survival is unknown. Therefore, we evaluated whether neoadjuvant therapy ...

Tumor immune microenvironment-based therapies in pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by ...

Innate and adaptive immune-directed tumour microenvironment in ...

Pancreatic cancer and pancreatic ductal adenocarcinoma are sometimes used interchangeably. Only 11% of patients with PDAC survive for at least 5 ...

Tumor Microenvironment Immune Response in Pancreatic Ductal ...

Whether neoadjuvant therapy-induced tumor immune response contributes to the improved survival is unknown. Therefore, we evaluated whether ...

The Tumor Immune Microenvironment in Pancreatic Ductal ... - MDPI

Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic tumor and is associated with poor prognosis and treatment response.

Immunologic Strategies in Pancreatic Cancer: Making Cold Tumors ...

The rising incidence and persistent dismal 5-year overall survival of pancreatic ductal adenocarcinoma (PDAC) highlight the need for new ...

Tumour microenvironment of pancreatic cancer: immune landscape ...

The role of the immune microenvironment of pancreatic cancer as an important prognostic/predictive feature is starting to emerge. PDAC is ...

Pancreatic ductal adenocarcinoma immune microenvironment and ...

MDSCs are a heterogeneous population of immature bone-marrow-derived cells able to suppress immune responses in TME. Pancreatic cancer cells can induce the ...

An integrated overview of the immunosuppression features in the ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies. It is characterized by a complex and immunosuppressive tumor microenvironment (TME) ...

Prognostic value of immune factors in the tumor microenvironment of ...

Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor with a highly immunosuppressive tumor microenvironment (TME) and is considered a highly ...

Crosstalk between the Tumor Microenvironment and Immune ...

Crosstalk between the Tumor Microenvironment and Immune System in Pancreatic Ductal Adenocarcinoma: Potential Targets for New Therapeutic ...

Dynamic profiling of immune microenvironment during pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) has little response to immune checkpoint inhibitors. An in-depth understanding of the immune microenvironment from a ...

Context-Specific Determinants of the Immunosuppressive Tumor ...

Immunotherapies have shown benefits across a range of human cancers, but not pancreatic ductal adenocarcinoma (PDAC). Recent evidence suggests that the ...

The role of innate immune cells as modulators of the tumor ...

The tumor microenvironment of pancreatic cancer, which comprises pancreatic cancer cells, stromal cells, and immune cells, as well as a ...

Targeting the tumor microenvironment for pancreatic ductal ...

The microenvironment of PDAC, which promotes tumorigenesis, disease development and metastasis, consists of fibroblasts, immune cells, pancreatic stellate ...

Quantitative Spatial Profiling of Immune Populations in Pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent type of pancreatic cancer accounting for over 90% of all pancreatic malignancies diagnosed (2).

Treatment hurdles, tumor microenvironment and immunotherapy

Combination treatments of chemotherapy, immunotherapy and radiation might render pancreatic ductal adenocarcinoma microenvironment more ...

The tumor immune microenvironment in pancreatic ductal ...

... Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic tumor and is associated with poor prognosis and treatment response. The tumor ...

Role of Immune Microenvironment in Pancreatic Ductal ... - MDPI

... immunosuppressive tumor microenvironment ... The tumors were staged according to the TNM classification system for pancreatic carcinoma ...