Tumour microenvironment of pancreatic cancer

The tumour microenvironment in pancreatic cancer - Nature

Metastatic pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumours despite the use of multi-agent conventional ...

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and ...

Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment with remarkable cellular and spatial heterogeneity ...

Pancreatic cancer tumor microenvironment is a major therapeutic ...

We discuss the complex network of microenvironment molecular and cellular composition and explore how they can be targeted to overcome immuno-therapeutic ...

Tumour microenvironment of pancreatic cancer: immune landscape ...

This review focuses on the characteristics of the local immune contexture of pancreatic ductal adenocarcinoma and the interaction between tumour cells and ...

Role of the tumor microenvironment in pancreatic cancer - PMC

The tumor microenvironment in pancreatic cancer contributes to tumor growth, invasion, and metastasis in a multifaceted way, including immune evasion. New ...

Pancreatic Tumor Microenvironment - ScienceDirect.com

The pancreatic tumor microenvironment is rich in growth factors and inflammatory cytokines that support tumor growth, and it is highly immunosuppressive. Up- ...

An integrated overview of the immunosuppression features in the ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies. It is characterized by a complex and immunosuppressive tumor microenvironment (TME) ...

Context-Specific Determinants of the Immunosuppressive Tumor ...

Despite significant advances in treating many tumor entities, therapeutic outcomes for patients with pancreatic ductal adenocarcinoma (PDAC) have remained ...

Tumor microenvironment participates in metastasis of pancreatic ...

This review discusses pancreatic cancer microenvironment formation and the mechanisms by which the microenvironment participates in metastasis.

The Pancreatic Tumor Microenvironment Is a Promising Target With ...

The pancreatic tumor microenvironment, a promising target for drug development with numerous potentially actionable pathways, ...

Tumor immune microenvironment-based therapies in pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by ...

Tumor Microenvironment - The Pancreas - Wiley Online Library

Summary. Pancreatic ductal adenocarcinoma (PDAC), one of the most devastating cancers of our time, has a dismal prognosis. PDAC is characterized ...

Clinical Strategies Targeting the Tumor Microenvironment of ... - MDPI

Pancreatic cancer has a complex tumor microenvironment which engages in extensive crosstalk between cancer cells, cancer-associated fibroblasts, and immune ...

The tumor microenvironment in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies and is characterized by a unique tumor microenvironment (TME) ...

Heterogeneous tumor microenvironment in pancreatic ductal ...

Heterogeneous tumor microenvironment in pancreatic ductal adenocarcinoma: An emerging role of single-cell analysis

Tumor microenvironment in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma with an associated tumor microenvironment · PDAC displays unique immunologic hallmarks. · In addition to CAFs, ...

Pancreatic Cancer Microenvironment and Cellular Composition

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal human solid tumors, despite great efforts in improving therapeutics over the past few ...

The Paradoxical Web of Pancreatic Cancer Tumor Microenvironment

This review will discuss the multiple components of the TME, their specific impact on tumorigenesis, and the multiple therapeutic targets.

Tumor Microenvironment | Pancreatic Cancer Drug Development

Understanding the area surrounding and feeding a pancreatic tumor cell, (the tumor microenvironment) provides an opportunity to develop therapeutic agents.

Physico-chemical characterization of the tumour microenvironment ...

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive lethal malignancy that accounts for more than 90% of pancreatic cancer diagnoses.