Tuning mitochondrial structure and function to criticality by ...

Tuning mitochondrial structure and function to criticality by ... - Nature

Alterations in network complexity were also accompanied by changes in key regulatory proteins as well as ATP and ROS production in the ...

(PDF) Tuning mitochondrial structure and function to criticality by ...

Furthermore, pathologically low or high variability moved mitochondria away from percolation which reduced the effectiveness of the electron transport chain by ...

Tuning mitochondrial structure and function to criticality by ... - OUCI

AbstractCells in vascular walls are exposed to blood pressure variability (BPV)-induced cycle-by-cycle fluctuations in mechanical forces which vary ...

Tuning mitochondrial structure and function to criticality ... - Altmetric

Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction · Scientific Reports, January 2020 · 10.1038/s41598-019-57301 ...

Common methods in mitochondrial research (Review) - PMC

Abnormalities in mitochondrial structure and function can lead to a variety of intracellular signaling cascades, oxidative stress and the initiation of ...

Remodeling of mitochondrial morphology and function: an emerging ...

The increased sensitivity to cell death as well as the structural and functional remodeling of the mitochondrial network described in previous sections are ...

Matrix stiffening promotes perinuclear clustering of mitochondria

... mitochondrial dynamics and ... Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction.

Mechanometabolism: Mitochondria promote resilience under pressure

∙ Suki, B. Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction. Sci. Rep. 2020; 10:407.

The Functional Impact of Mitochondrial Structure Across Subcellular ...

In a cell, mitochondrial shapes and dynamics are finely tuned by fusion and fission proteins whose molecular actions are dependent on the presence of GTP.

Super-resolution microscopies, technological breakthrough to ...

Nowadays, the molecular mechanisms linking mitochondrial structure and dynamics to their physiological roles are progressively being revealed allowing us to ...

Universal dynamics of mitochondrial networks: a finite-size scaling ...

Evidence from models and experiments suggests that the networked structure observed in mitochondria emerges at the critical point of a phase ...

[PDF] Regulation of mitochondrial network architecture and function ...

Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction · Medicine, Engineering. Scientific Reports · 2020.

Spatiotemporal Modeling of Mitochondrial Network Architecture

Individual mitochondria transition between fragmented units and highly connected tubular structures. This study shows how the network's ...

Synthetic Control of Mitochondrial Dynamics: Developing Three ...

Often referred to as the powerhouse of the cell, the mitochondria have a well-defined but complicated structure with important functional ...

Mitochondrial function in the heart: the insight into mechanisms and ...

In addition, well-controlled mitochondrial dynamics are critical for the maintenance of mitochondrial morphology and distribution, which is ...

Force-induced tail-autotomy mitochondrial fission and biogenesis of ...

Mitochondria are double-membranous organelles critical for cell survival and death. They constantly fuse and divide to maintain mitochondrial functions.

Mitochondrial Structure and Function Are Disrupted by Standard ...

Mitochondria regulate critical components of cellular function via ATP production, reactive oxygen species production, Ca2+ handling and apoptotic signaling ...

A Comprehensive Platform for Mitochondrial Structure Segmentation ...

Consequently, quantitative analysis of the inner cristae not only reveals the functional state of mitochondria but also highlights its role in ...

Methods to Evaluate Changes in Mitochondrial Structure and ... - MDPI

Additional processes affected by mitochondrial function and signaling include cell proliferation and apoptosis [5]. Given the central role of mitochondria in ...

Exploring Age-Related Changes in Mitochondrial Structure and ...

- Broader Implications for Aging and Metabolic Health: By studying mitochondrial structure across different tissues and species, the team hopes to gain a deeper ...