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Two|state conformations in the hyaluronan|binding domain regulate ...


Two-state conformations in the hyaluronan-binding domain regulate ...

The hyaluronan (HA) receptor CD44 mediates cell adhesion in leukocyte trafficking and tumor metastasis. Our previous nuclear magnetic ...

Article Two-State Conformations in the Hyaluronan-Binding Domain ...

Article. Two-State Conformations in the Hyaluronan-Binding Domain Regulate CD44 Adhesiveness under Flow Condition.

Two-State Conformations in the Hyaluronan-Binding Domain ...

The hyaluronan (HA) receptor CD44 mediates cell adhesion in leukocyte trafficking and tumor metastasis. Our previous nuclear magnetic resonance (NMR) ...

Two-state conformations in the hyaluronan-binding domain regulate ...

Semantic Scholar extracted view of "Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition.

Mechanical force effect on the two-state equilibrium of the ... - PNAS

S Ogino, et al., Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition. Structure 18, 649–656 (2010) ...

Two-State Conformations in the Hyaluronan-Binding Domain ...

Two-State Conformations in the Hyaluronan-Binding. Domain Regulate CD44 Adhesiveness under Flow Condition. Shinji Ogino,1 Noritaka Nishida,1 Ryo Umemoto,1 ...

Identification of two hyaluronan-binding domains in the hyaluronan ...

... control binding activity the NaCl concenof when assay. The truncated RHAMM ... The interaction between HA and RHAMM does not appear to rely onthe conformation ...

Molecular Dynamics Simulation Study on Allosteric Regulation of ...

Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition. Structure 2010, 18, 649– 656, DOI ...

The regulation and function of hyaluronan binding by CD44 in the ...

... HA 20. This raises the interesting possibility that CD44 may exist in two conformational states in cells (a high and low affinity state) ...

Structure of the Regulatory Hyaluronan Binding Domain ... - Cell Press

Of these, two residues (residues 107 and 112 of chain A) were in weak electron density, and their conformations were reset so as to better agree with the ...

DNA-binding proteins from MBD through ZF to BEN: recognition of ...

... two conformations. Xing Zhang ... Members of the BEN domain proteins bind CGCG or CACG elements within CGIs to regulate gene expression.

Conformational motions and ligand-binding underlying gating and ...

The solenoid scaffold includes domains responsible for binding of ligands and regulatory ... In each state, the ARM2 domain displayed the ...

Enhancing response of a protein conformational switch by using two ...

... domain can be used to control the AFF-mediated conformational ... Assuming two-state character for all folding/unfolding reactions, the Bn domain ...

Conformational heterogeneity of the BTK PHTH domain drives ...

BTK, a TEC-family tyrosine kinase activated by the B-cell antigen receptor, contains a variety of regulatory domains and it is subject to ...

Biased localization of actin binding proteins by actin filament ...

Two mechanisms regulate ... αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly ...

Transient conformations in the unliganded FK506 binding domain of ...

Figure 7 Two-state population analysis of the experimental wildtype FKBP51 domain and K58T variant hydrogen exchange. Assuming a single ...

PDZ domains and their binding partners: structure, specificity, and ...

... conformation of the PDZ domain and to regulate its function. Phosphorylation on the PDZ domain itself negatively modulates PDZ interactions.

A lac Repressor Case Study - Diva Portal

1,23,28,29 Such a two-state model for protein−. DNA binding has ... conformational space of the two DNA-binding domains.43. Here, we ...

Two conformations of the integrin A-domain (I-domain) - Cell Press

The interactions of several integrins with their extracellular ligands are mediated by an A-type domain (generally called the I-domain in integrins). Binding of ...

Two distinct conformations of factor H regulate discrete complement ...

The maximum binding responses were used to fit a steady-state affinity model. ... Identification of a heparin binding domain in the seventh short consensus repeat ...