Un|gating and allosteric modulation of a pentameric ligand ...

Un-gating and allosteric modulation of a pentameric ligand ... - PLOS

Here, we provide the first atomistic description of the transition from open to closed (un-gating) in the glutamate-gated chloride channel (GluCl) from ...

Un-gating and allosteric modulation of a pentameric ligand-gated ...

Pentameric ligand-gated ion channels (pLGICs) mediate intercellular communication at synapses through the opening of an ion pore in response ...

Un-gating and allosteric modulation of a pentameric ligand-gated ...

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics. Nicolas E Martin, Data curation, Formal analysis ...

Un-gating and allosteric modulation of a - ProQuest

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics. Martin, Nicolas E; Malik, Siddharth; Calimet ...

(PDF) Un-gating and allosteric modulation of a pentameric ligand ...

PDF | Pentameric ligand-gated ion channels (pLGICs) mediate intercellular communication at synapses through the opening of an ion pore in ...

Un-gating and allosteric modulation of a pentameric ... - Altmetric

Nicolas E Martin, Siddharth Malik, Nicolas Calimet, Jean-Pierre Changeux, Marco Cecchini · Pentameric ligand-gated ion channels (pLGICs) mediate intercellular ...

Allosteric Modulation of the Pentameric Ligand-Gated Ion Channel ...

Pentameric ligand-gated ion channels (pLGICs) or Cys-loop receptors are a class of ion channels involved in fast synaptic transmission in ...

3D structure and allosteric modulation of the transmembrane ...

Pentameric ligand-gated ion channels (pLGICs) are transmembrane protein complexes that mediate chemical communication between cells in both the central and ...

Structural basis for allosteric transitions of a multidomain pentameric ...

This illustrates the different ways allosteric modulation can occur in the gating transition of pLGICs. Abstract. Pentameric ligand-gated ion channels (pLGICs) ...

Un-gating and allosteric modulation of a pentameric ligand ... - OUCI

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics. https://doi.org/10.1371/journal.pcbi.1005784 ...

Structural basis for the modulation of pentameric ligand-gated ion ...

Pentameric ligand-gated ion channels (pLGICs) mediate and modulate fast synaptic communication. •. pLGIC function is modulated by membrane lipids and other ...

Allosteric modulation of pentameric ligand gated ion channels

Download Citation | Allosteric modulation of pentameric ligand gated ion channels : from the jiggling of atoms to neuropharmacological strategies | Les ...

Allosteric modulation of pentameric ligand-gated ion channels by ...

Allosteric modulation of pentameric ligand-gated ion channels by general anesthetics. Heusser, Stephanie A. Stockholm University, Faculty of ...

Allosteric regulation of pentameric ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical ...

Allosteric Modulation of the Pentameric Ligand-Gated Ion Channel ...

Muscle type nicotinic acetylcholine receptors (nAChRs) are heteropentameric ligand-gated ion channels composed of four homologous subunits (2a, ...

Structural basis for allosteric transitions of a multidomain pentameric ...

allosteric gating transitions in this ... allosteric mechanism of general anesthetic modulation in pentameric ligand-gated ion channels.

3D structure and allosteric modulation of the transmembrane ...

Semantic Scholar extracted view of "3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels" by J.

3D structure and allosteric modulation of the transmembrane ...

Pentameric ligand-gated ion channels mediate rapid chemo-electric signal transduction in animals. The active site of this family of proteins is their ion ...

Allosteric Activation and Modulation of Pentameric Ligand-gated Ion ...

Allosteric Activation and Modulation of Pentameric Ligand-gated Ion Channels. Tuesday, April 30, 2013. Eukaryotic Cys-loop receptors control fast synaptic ...

Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion ...

Interestingly, some of these sites are also known sites of action for other allosteric modulators or drugs, supporting the hypothesis that lipids modulate ...