Understanding sex differences in autoimmune disease

The activity of a type of RNA called Xist may help explain why autoimmune diseases are more common in women than men.

Sex differences in autoimmune disease | Nature Immunology

Autoimmune diseases are more prevalent in women than men. A new interest in understanding the biology of this difference as well as funding opportunities

Mechanisms underlying sex differences in autoimmunity - JCI

What constitutes an autoimmune disease depends on how they are defined (6), with the number of autoimmune diseases varying from 80 to 120 or ...

Sex differences in autoimmune diseases - PMC - PubMed Central

Indeed, being female confers a greater risk of developing these diseases than any single genetic or environmental risk factor discovered to date. Understanding ...

Sex and gender influence on immunity and autoimmunity - Frontiers

Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.

Sex-based differences in autoimmune diseases - ISS

Symptom severity, disease course, response to therapy and overall survival may also differ between males and females with autoimmune diseases. Sex hormones have ...

Gender differences in autoimmune disease - ScienceDirect.com

For most autoimmune diseases there is a clear sex difference in prevalence, whereby females are generally more frequently affected than males.

Unravelling sex differences in autoimmune diseases - 360 - 360info

Autoimmune diseases are a leading cause of death in women under 65, and they're four times more likely to develop in females than males.

Center for Sex-based Differences in the Immune System

Women are better at fighting off infection but are more likely to develop an autoimmune condition, with 80 percent of autoimmune disease cases diagnosed in ...

Unravelling sex differences in autoimmune diseases - UNSW Sydney

Autoimmune diseases are a leading cause of death in women under 65, and they're four times more likely to develop in females than males.

Why women have more autoimmune diseases than men

Moreover, a recent study showed that sex hormones strongly influence thymic epithelial cell biology, providing a strong mechanistic explanation ...

Sex Differences in Autoimmune Disease from a Pathological ...

The reason for the high prevalence in women is unclear. Women are known to respond to infection, vaccination, and trauma with increased antibody production and ...

Sex differences in immune responses | Nature Reviews Immunology

In this Review the authors discuss some of the key differences that exist between male and female immune functions.

Sex Bias and Autoimmune Diseases - ScienceDirect.com

Many studies have connected increased risk of autoimmune disease development and severity with estrogen exposure. Polymorphisms of the different estrogen ...

Mechanisms of sex hormones in autoimmunity: focus on EAE

Sex-related differences in the occurrence of autoimmune diseases is well documented, with females showing a greater propensity to develop ...

Sex bias in lymphocytes: Implications for autoimmune diseases

This is, at least in part, due to sex-dependent differences in the immune system that are influenced by the complex interplay between sex hormones and sex ...

Investigating sex differences in T regulatory cells from cisgender and ...

Statistically significantly elevated frequencies of Treg cells were one of the top immune-cell features differentiating young post-pubertal ...

OP0013 SEX DIFFERENCES IN AUTOIMMUNE DISEASE ...

Males have a lipoprotein profile associated with increased CVR, but a more anti-inflammatory immune profile compared to females. Together, this could explain ...

Sex Differences in Autoimmune Disease - BioMed Central

This includes dissecting the influence of the innate and adaptive immune system on cardiovascular remodeling, understanding the dynamics and function of bio- ...

(PDF) Sex differences in autoimmune disease - ResearchGate

Autoimmune diseases are more prevalent in women than men. A new interest in understanding the biology of this difference as well as funding ...