Unveiling the Molecular Mechanisms Linking Aging with ...

Unveiling the molecular mechanisms linking aging with ...

Aging is a major risk factor for neurodegenerative diseases, but the molecular mechanisms behind this relationship are not clear.

Researchers from Japan explored the role of PQBP3, a protein that helps stabilize the nuclear membrane, in cellular senescence and neurodegeneration.

Unveiling the molecular mechanisms linking aging with ... - IBCCES

In a recent study, researchers explored the role of PQBP3, a protein that helps stabilize the nuclear membrane, in cellular senescence and ...

Epigenetics: Linking Nutrition to Molecular Mechanisms in Aging

Recent studies suggest that epigenetic mechanisms are responsible for life span and the progression of aging.

Aging and aging-related diseases: from molecular mechanisms to ...

Lysosomal protein hydrolysis is reduced during aging, which impairs autophagy, exacerbates cellular damage, and promotes the development of age- ...

Immunosenescence: molecular mechanisms and diseases - Nature

This chronic inflammation is a typical phenomenon linked to immunosenescence and it is considered the major risk factor for age-related diseases ...

Unveiling the molecular landscape of cognitive aging: insights from ...

These findings provide valuable insights into the biological mechanisms underlying the association between WM coherence and cognitive aging.

Revealing a master controller of development and ageing

IMB researchers have unlocked crucial molecular secrets of ageing in ... “By pinpointing AP-1 as a master controller linked to ageing ...

A multiomic atlas of the aging hippocampus reveals molecular ...

Epigenetic mechanisms have important roles across a wide spectrum of brain-related processes, ranging from core biological events such as ...

Review article The molecular mechanism of aging and the role in ...

According to a genome-wide analysis, around 57 genetic loci are linked to lifespan. Cellular performance and stress resistance are affected by ...

Unveiling the molecular basis of intrinsic skin aging1 - 2005

In this study, the molecular changes of intrinsic skin aging were analyzed by applying 'Serial Analysis of Gene Expression' (SAGETM) to skin ...

Cellular and Molecular Changes During Aging in MEC - bioRxiv

These findings help us to understand the cellular and molecular changes in the MEC in healthy aging animals and the changes of Bglap3+ cells in ...

Modelling the molecular mechanisms of aging - Portland Press

Since mitochondrial dysfunction leads to an increase in oxidative stress, impaired energy and inhibits autophagy, linking models of mitochondrial damage and ROS ...

Molecular mechanisms linking the evolutionary conserved TORC1 ...

The knowledge on the molecular aspects regulating ageing in eukaryotic organisms has benefitted greatly from studies using the budding yeast Saccharomyces ...

Growth and aging: a common molecular mechanism

It is commonly assumed that growth and aging are somehow linked, but the nature of this link has been elusive. Here we review the aging process as a ...

Cell Aging: Molecular Mechanisms and Implications for Disease

Linking these different determinants of aging with disease, this volume aims to reveal their multiple interdependencies. We see that there is no single “perfect ...

Editorial: Genetic and molecular mechanisms of healthy aging and ...

Recent studies have explored the molecular pathways behind aging, focusing on key systems such as the respiratory tract, muscles, immune system, and stress ...

Identification of molecular mechanisms underlying frailty and ...

We validated their expression in different cohorts as well as after different types of interventions and we discovered their role in cell aging; overall, ...

Aging: From Molecular Mechanisms, Pathophysiology to Novel ...

This Special Issue, “Aging: From Molecular Mechanisms, Pathophysiology to Novel Therapeutic Approaches”, will discuss the current state of the art, challenges, ...

Mechanisms of Ageing and Development - ScienceDirect.com

Mechanisms of Ageing and Development is a multidisciplinary journal aimed at revealing the molecular, biochemical and biological mechanisms that underlie the ...