Update on Emerging Therapies for Advanced Colorectal Cancer

Novel biomarker-driven approaches in the management of patients with advanced colorectal cancer are leading to improvements in outcomes.

Chemotherapy has been the backbone of systemic treatment of advanced CRC, but utility has been limited because of invariable resistance to therapy.

Update on Emerging Therapies for Advanced Colorectal Cancer

Information ... Permissions. Request permissions for this article. Request permissions. Authors ... Notes. Olatunji B. Alese, MD, FWACS, Department of Hematology ...

Current and emerging therapeutic approaches for colorectal cancer

In patients with metastatic CRC, two phase III randomized studies compared capecitabine as a single drug to the typical 5-FU/LV therapy combination, and the RR ...

Current and Emerging Treatment Paradigms in Colorectal Cancer

The treatment of unresectable metastatic colorectal cancer ... metastatic colorectal cancer: Updated survival results and subgroup analyses from the BEACON study.

A perspective on emerging therapies in metastatic colorectal cancer ...

Metastatic colorectal cancer incidence are on the rise due to a tiny percentage of tumors developing resistant to medicines despite advances in treatment ...

Advances in Colorectal Cancer Research - NCI

Treatment for Colorectal Cancer · Immunotherapy for patients with Lynch syndrome or MSI-H colorectal cancer · Combining immunotherapy with other ...

Editorial: New therapeutic approaches in microsatellite stable ...

... therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer ... Update on emerging therapies for advanced colorectal cancer.

Patients With Metastatic Colorectal Cancer May Continue Benefitting ...

Seven of the eight patients whose tumors progressed after stopping treatment were placed back on ICI therapy. Of note, all seven patients ...

A Variety of Treatment Options Are Becoming Available in CRC

... treatment updates, molecular testing options, and emerging targets in the world of metastatic colorectal cancer (CRC). She discussed these ...

Update on Targeted Therapy and Immunotherapy for Metastatic ...

Bevacizumab has been available for nearly two decades. Bevacizumab is often added to chemotherapy regimens to treat metastatic colorectal cancer and is ...

Update on Emerging Therapies for Advanced Colorectal Cancer

Tumors that are mismatch repair-deficient have demonstrated remarkable response to immune checkpoint inhibitor therapy. However, most CRC tumors ...

An Update on the Current and Emerging Targeted Agents in ...

Over the past 8 to 10 years, significant advances have been made in the treatment of metastatic colorectal cancer (mCRC). In particular, the development of ...

Comprehensive review of targeted therapy for colorectal cancer

Meanwhile, the 5-year survival rate for CRC is ~64%, but drops to 12% for metastatic CRC, and further investigation is still required to develop ...

New developments in targeted therapy for metastatic colorectal cancer

Recent advancements in translational research have led to the identification of several new therapeutic targets and improved the treatment ...

Metastatic colorectal cancer: mechanisms and emerging therapeutics

While early-stage colorectal cancer (CRC) can be cured by surgery with or without adjuvant chemotherapy, mCRC cannot be eradicated due to a large burden of ...

Current and emerging therapies for metastatic colorectal cancer

The use of bevacizumab as part of first-line therapy for metastatic colorectal cancer is well established, but there is no clinical experience ...

End of Year Review in CRC: Exploring Emerging Treatment Options ...

This insightful review includes a focus on the recent approval of fruquintinib and important updates on target therapies for HER2+, BRAF V600E-Mutant, and KRAS ...

Navigating the Latest Metastatic Colorectal Cancer Treatments and ...

Emerging Clinical Trials for Metastatic Colorectal Cancer Patients. Dr. Eng: For the MSI-high patient population, there should be some updates ...

Advanced colorectal cancer: New immunotherapy combo may be ...

Hard-to-treat cancers · Encouraging results from immunotherapy against colorectal cancer · Liver tumors reduced treatment efficacy · Manageable ...