Use of Incretin Therapy in the Treatment of Type 2 Diabetes Mellitus

Incretin-Based Therapies for the Treatment of Type 2 Diabetes

It exerts its glucoregulatory actions through prevention of incretin degradation, leading to potentiation of GLP-1 and GIP action (6). Sitagliptin is ...

This article reviews the similarities, differences, advantages, and disadvantages of the incretin therapies.

Incretin-based therapies for type 2 diabetes mellitus - PubMed

Incretin-based drugs, such as glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase 4 inhibitors, are now routinely used to treat type 2 ...

Incretin Based Treatments - Diabetes Education Online - UCSF

Incretin based treatments reduce post meal blood sugars. These medicines are also euglycemics, which help return the blood sugar to the normal range.

Use of Incretin Therapy in the Treatment of Type 2 Diabetes Mellitus

The incretin therapies activate pancreatic β-cell secretion of insulin exclusively in the presence of elevated blood sugar. This is an important concept as this ...

Exenatide and liraglutide are the two GLP-1 agonists currently approved for use in the United States. Exenatide is a synthetic version of ...

Incretin-Based Therapies in Type 2 Diabetes Mellitus

Two new drugs, exenatide (GLP-1 mimetic) and sitagliptin [dipeptidyl peptidase (DPP) 4 inhibitor], have been approved by regulatory agencies for treating T2DM.

Incretin-based therapy: a powerful and promising weapon in the ...

Incretin-based treatment modalities, and in particular glucagon-like peptide 1 (GLP-1) receptor agonists, are able to successfully counteract several of the ...

Incretin-Based Therapies: Viewpoints on the way to consensus

Treatment with GLP-1 receptor agonists (“incretin mimetics”) and DPP-4 inhibitors (“incretin enhancers”) are based on antidiabetic properties of ...

Clinical Application of Incretin-Based Therapy: Therapeutic Potential ...

Early use of these agents may be effective in preventing diabetes in those at risk, or in halting or retarding disease progression in patients with frank ...

Use of Incretin Therapy in the Treatment of Type 2 Diabetes Mellitus

Cite this ... Use of Incretin Therapy in the Treatment of Type 2 Diabetes Mellitus. / Zappas, Michelle P.; Gentes, Meredith; Walton-Moss, Benita. In: Journal for ...

Emerging role of insulin with incretin therapies for management of ...

Type 2 diabetes mellitus (T2DM) is a progressive disease warranting intensification of treatment, as beta-cell function declines over time.

Incretin-based therapies for type 2 diabetes mellitus - ResearchGate

The use of incretin-based therapies in hospitalized patients with diabetes is attractive because of their metabolic effects, such as increasing insulin ...

Incretin-Based Therapy for Diabetes: What a Cardiologist Needs to ...

Incretin-based therapies are effective glucose-lowering drugs that have an increasing role in the treatment of type 2 diabetes because of ...

Clinical Application of Incretin-Based Therapy: Therapeutic Potential ...

Incretin-Based Therapies for Diabetic Complications - MDPI

The beneficial effects of GLP-1RA on albuminuria in type 2 diabetic patients have also been reported. For instance, long-term treatment (one-year) of ...

Comparison of efficacy between incretin-based therapies for type 2 ...

Effective weight loss, lack of significant hypoglycaemia, and favourable cardiometabolic profile make Incretin based therapies an attractive ...

Effect of Long-term Incretin-Based Therapies on Ischemic Heart ...

Patients with type 2 diabetes mellitus (T2DM) experience many cardiovascular complications. Several studies have demonstrated the ...

Incretin-based therapies in the treatment of type 2 diabetes

Data obtained indicate that GLP-1 agonists and DPPIV inhibitors could increase the risk of pancreatitis and pancreatic cancer, possibly due to their capacity to ...

Incretin-based medications transforming treatment of type 2 diabetes ...

The development of incretin-based molecules has led to therapies that can induce greater reductions in HbA1c and body weight for people with ...