Using patient|derived organoids to predict locally advanced or ...

Using patient-derived organoids to predict locally advanced or ...

Predicting the clinical response to chemotherapeutic or targeted treatment in patients with locally advanced or metastatic lung cancer ...

Using patient-derived organoids to predict locally advanced or ...

generated lung cancer organoids (LCOs) derived from human malignant serous effusions and tissues. The LCOs accurately represented original tumor features. Drug ...

Patient-derived organoids to predict the drug response in locally ...

Background: Lung cancer organoids (LCOs) were expected to be the potential precision medicine approach for clinical response prediction.

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Here we generate a living organoid biobank from patients with locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiation ...

Using patient-derived organoids to predict locally advanced or ...

Abstract and Figures. Predicting the clinical response to chemotherapeutic or targeted treatment in patients with locally advanced or metastatic lung cancer ...

The Efficacy of Using Patient-Derived Organoids to Predict ... - MDPI

Patient-derived tumour organoids are three-dimensional, self-organising cultures of tumour cells isolated from surgical or endoscopic tissue samples [13]. They ...

Patient-Derived Organoids Predict Chemoradiation Responses of ...

Here we generate a living organoid biobank from patients with locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiation (NACR) enrolled in a ...

Patient-derived organoids as a predictive biomarker for treatment ...

Effective predictive biomarkers are needed to enable personalized medicine and increase treatment efficacy and survival for cancer patients, ...

Review Patient-derived organoids in precision cancer medicine

Generally, organoid models originate from induced PSCs (iPSCs) or ASCs. The development of disease-specific organoids due to gene mutations can ...

Patient-derived tumor organoids: a new avenue for preclinical ...

PDTO can also be isolated from normal organoids via phenotype-based manual selection or via clonal expansion by using cell sorting. However, all ...

Using patient-derived organoids to predict locally advanced or ...

Predicting the clinical response to chemotherapeutic or targeted treatment in patients with locally advanced or metastatic lung Cancer requires ...

Using patient-derived organoids to predict locally advanced or ...

Using patient-derived organoids to predict locally advanced or metastatic lung cancer tumor response: A real-world study · List of references · Publications that ...

Advances of Patient-Derived Organoids in Personalized Radiotherapy

Patient-derived organoids (PDO), based on the advanced three-dimensional (3D) culture technology, can provide more relevant physiological and ...

Patient-Derived Organoids from Locally Advanced Gastric ...

These patient tumor-derived organoids (PDOs) are in vitro models that can recapitulate the pathophysiology of the original tumors along with ...

Modeling Clinical Responses to Targeted Therapies by Patient ...

However, clinical relevance of advanced lung adenocarcinoma organoids remains unknown. Here, we examined the ability of PDOs to predict clinical ...

Clinical Relevance of Patient-Derived Organoid of Surgically ...

The establishment and growth rates of LTOs were associated with the histologic subtype and tumor size. LTOs derived from resected specimens have ...

Implementing patient derived organoids in functional precision ...

Patient Derived Organoids (PDOs) emerged as the best technology to develop ex vivo tumor avatars. Whether drug testing on PDOs to identify ...

Organoids for Functional Precision Medicine in Advanced ...

Patient-derived organoids (PDOs) are promising tumor avatars that could enable ex vivo drug tests to personalize patients' treatments in the frame of ...

Patient-Derived Organoids from Locally Advanced - ProQuest

A minority of patients do not respond to chemotherapy and thus may benefit from upfront surgery. Patient-derived organoids (PDOs) are an in vitro model that may ...

Patient‐Derived Organoids Can Guide Personalized‐Therapies for ...

Patient‐Derived Organoids Can Guide Personalized‐Therapies for Patients with Advanced Breast Cancer · Ping Chen, Xu Zhang, +31 authors. Chuxia Deng · Published in ...