Validation of a Bioinformatics Workflow for Routine Analysis of ...

Despite being a well-established research method, the use of whole-genome sequencing (WGS) for routine molecular typing and pathogen characterization ...

We present a validation strategy focusing specifically on the exhaustive characterization of the bioinformatics analysis of a WGS workflow.

Neisseria meningitidis as a Proof-of-Concept - PubMed

Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National ...

[PDF] Validation of a Bioinformatics Workflow for Routine Analysis of ...

This work presents a validation strategy focusing specifically on the exhaustive characterization of the bioinformatics analysis of a WGS workflow designed ...

A Practical Bioinformatics Workflow for Routine Analysis of Bacterial ...

For the evaluation of workflow repeatability and reproducibility, the bioinformatics workflow was run twice on the same dataset in the same and different ...

Validation strategy of a bioinformatics whole genome sequencing ...

Validation strategy of a bioinformatics whole genome sequencing workflow for Shiga toxin-producing Escherichia coli using a reference collection ...

Validation of a Bioinformatics Workflow for Routine Analysis of ...

Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European ...

Validation strategy of a bioinformatics whole genome sequencing ...

Validation strategy of a bioinformatics whole genome sequencing workflow for Shiga toxin-producing Escherichia coli using a reference collection extensively ...

A Bioinformatics Whole-Genome Sequencing Workflow for Clinical ...

The validation framework for our WGS-based bioinformatics workflow can aid in the standardization of bioinformatics tools by the MTB community and other SNP- ...

A Practical Bioinformatics Workflow for Routine Analysis of Bacterial ...

No errors were reported during the execution period, and all genomes were analysed. The bioinformatics workflow can be tailored to other pathogens of interest ...

Development and Validation of a Bioinformatic Workflow for ... - MDPI

However, the bioinformatics analysis tools designed for rapid analysis of these sequencing datasets are not developed with this application in ...

(PDF) Validation of a Bioinformatics Workflow for Routine

Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European.

Development and validation of a bioinformatics... | Posters

The use of whole-genome sequencing (WGS) for routine molecular typing and pathogen characterization in public health remains a substantial ...

An ISO-certified genomics workflow for identification and ... - Nature

Here, we report the creation and validation of abritAMR, an ISO-certified bioinformatics platform for genomics-based bacterial AMR gene detection.

Bioinformatics Workflow for Whole Genome Sequencing

The bioinformatics workflow for WGS falls into the following steps: (1) raw read quality control; (2) data preprocessing; (3) alignment; (4) variant calling; ( ...

Standards and Guidelines for Validating Next-Generation ...

The workflow and design of the bioinformatics pipeline before validation should, therefore, take into account the intended use of the test, the analytes to ...

A Practical Bioinformatics Workflow for Routine Analysis of Bacterial ...

List of references. Bogaerts, Validation Strategy of a Bioinformatics Whole Genome Sequencing Workflow for Shiga Toxin-Producing Escherichia coli Using a ...

Validation strategy of a bioinformatics whole genome sequencing ...

The workflow supports three commonly used bioinformatics approaches for the detection of genes and alleles: alignment with blast+, kmer-based ...

Assembling and Validating Bioinformatic Pipelines for Next ...

Optimization of the pipeline should be performed during pipeline development and the workflows should be “lock-down” at the validation stage, ...

Recommendations for the Use of in Silico Approaches for Next ...

When a change is only made to the bioinformatics pipeline, a laboratory can help validate the change by using existing, unmodified data from its ...