- Validation of the Surrogate Threshold Effect for Change in Bone ...🔍
- Validation of the Surrogate Threshold Effect for Change in BMD as a ...🔍
- Validation of the Surrogate Threshold Effect for Change ...🔍
- an alternative measure for meta‐analytic surrogate endpoint validation🔍
- Bone mineral density as a surrogate endpoint for fracture risk ...🔍
- An alternative measure for meta|analytic surrogate endpoint validation🔍
- Surrogate threshold effect based on a meta|analysis ...🔍
- Surrogate endpoints🔍
Validation of the Surrogate Threshold Effect for Change ...
Validation of the Surrogate Threshold Effect for Change in Bone ...
The surrogate threshold effect (STE) is defined as the minimum treatment effect on a surrogate that is reliably predictive of a treatment effect on the ...
Validation of the Surrogate Threshold Effect for Change in Bone ...
The surrogate threshold effect (STE) is defined as the minimum treatment effect on a surrogate that is reliably predictive of a treatment ...
Validation of the Surrogate Threshold Effect for Change in BMD as a ...
The surrogate threshold effect (STE) is defined as the minimum treatment effect on a surrogate that is reliably predictive of a treatment effect ...
Validation of the Surrogate Threshold Effect for Change in BMD as a ...
... Recent analyses from the FNIH/SABRE project show that TH BMD gain with osteoporosis treatment is an excellent surrogate for antifracture ...
Validation of the Surrogate Threshold Effect for Change ... - Altmetric
Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH‐ASBMR SABRE Project.
Validation of the Surrogate Threshold Effect for Change in Bone ...
Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH-ASBMR SABRE Project.
an alternative measure for meta‐analytic surrogate endpoint validation
A new concept is introduced, the so‐called surrogate threshold effect (STE), defined as the minimum treatment effect on the surrogate necessary to predict a ...
Bone mineral density as a surrogate endpoint for fracture risk ...
Eastell, R ∙ Vittinghoff, E ∙ Lui, LY ∙ et al. Validation of the surrogate threshold effect for change in bone mineral density as a ...
An alternative measure for meta-analytic surrogate endpoint validation
We considered the correlation between OS and surrogate endpoints to be strong if the R 2 exceeded 0.75. 15, 16 The surrogate threshold effect ( ...
Surrogate threshold effect based on a meta-analysis ... - SpringerLink
According to the definition in IQWiG's rapid report, correlation was merely medium-sized and therefore the validity of the surrogate endpoint is ...
Surrogate endpoints: a key concept in clinical epidemiology
The surrogate endpoint should show a threshold effect, meaning that a specific change (or state) in the surrogate with an intervention (relative to the ...
Surrogate endpoints: a key concept in clinical epidemiology
The surrogate endpoint should show a threshold effect, meaning that a specific change (or state) in the surrogate with an intervention ...
Is blood pressure reduction a valid surrogate endpoint for stroke ...
They are reported as a relative measure and can take any value from 0 to 1. The surrogate threshold effect proportion (STEP), proposed by ...
Surrogate Threshold Effect. HPV. Human Papilloma Virus. CIN. Cervical ... Hence, more scientific and clinical knowledge is required for the validation of ...
Validation of surrogate end points for overall survival in advanced ...
association (correlation) to establish the validity of sur- rogate end points. (2) The surrogate threshold effects (STEs) reported in our article do take ...
In cases where no high correlation is evident, surrogate threshold effect ... validity if sufficiently large effects on the surrogate have been shown. It ...
A framework for the definition and interpretation of the use of ...
Current surrogate endpoint definitional frameworks are inconsistent and unclear. Surrogate endpoints are used in trials as a substitute of the treatment effects ...
[PDF] The validation of surrogate endpoints in meta-analyses of ...
This approach suggests a new method for the validation of surrogate endpoints, and naturally leads to the prediction of the effect of treatment upon the ...
The Strength of Association Between Surrogate End Points and ...
... surrogate end point and the change ... Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation.
Evaluation of pathological complete response as surrogate endpoint ...
STE=surrogate threshold effect; pCR=pathological complete response ... measure for meta-analytic surrogate endpoint validation. Pharm.