Visualizing transcription factor dynamics in living cells

In this review, we review current transcription imaging techniques and summarize converging results from various lines of research.

Visualizing transcription factor dynamics in living cells - PubMed

The assembly of sequence-specific enhancer-binding transcription factors (TFs) at cis-regulatory elements in the genome has long been ...

Transcription Factor Dynamics - PubMed

Advances in fluorescence microscopy have made it possible to visualize real-time TF dynamics in living cells, leading to two intriguing ...

Visualizing transcription factor dynamics in living cells - Bates College

Recent advances in imaging technologies now enable direct visualization of TF-driven regulatory events and transcriptional activities at the single-cell, single ...

Visualizing transcription: key to understanding gene expression ...

Transcription factor dynamics ... Recent developments in in vivo fluorescence microscopy have made it possible to directly 'see' the binding and ...

Visualizing transcription factor dynamics in living cells - Ex Libris

Recent advances in imaging technologies now enable direct visualization of TF-driven regulatory events and transcriptional activities at the single-cell, single ...

Visualizing transcription factor dynamics in living cells - ResearchGate

Recent advances in imaging technologies now enable direct visualization of TF-driven regulatory events and transcriptional activities at the single-cell, single ...

Visualizing transcription factor dynamics in living cells - Scite

Visualizing transcription factor dynamics in living cells · Abstract: Liu and Tjian review how superresolution and live-cell imaging are providing new insights ...

Live cell dynamics of the NF-Y transcription factor | Scientific Reports

Transcription factors (TFs) are core players in the control of gene expression, evolutionarily selected to recognise a subset of specific ...

Navigating the crowd: visualizing coordination between genome ...

Visualizing transcription factor dynamics in living cells. J. Cell Biol. 2018;217(4):1181-91. McNally JC, Müller WG, Walker D, Wolford R ...

Live‐cell imaging reveals the interplay between transcription factors ...

However, how nucleosomes regulate TF binding dynamics in vivo is still mostly unexplored. In addition, the relationship between TF binding dynamics and the ...

Advances in visualizing transcription factor – DNA interactions

Decades of molecular biology research have led to unprecedented insights into how TFs access the genome to regulate transcription. In the last 20 years, ...

Following the tracks: How transcription factor binding dynamics ...

We discuss different models that aim to link transient DNA binding by TFs to bursts of transcription and present an outlook for how future advances in ...

Visualizing transcription factor dynamics, one molecule at a time

However, with the advent of live-cell fluorescence microscopy imaging, it has been demonstrated that most of transcription factors interact very ...

Visualizing chromatin dynamics in intact cells - ScienceDirect.com

Live cell imaging and photobleaching studies of fluorescently-tagged proteins reveal that many transcription factors and other chromatin-associated proteins ...

Visualizing long-term single-molecule dynamics in vivo by stochastic ...

J Elf, GW Li, XS Xie, Probing transcription factor dynamics at the single-molecule level in a living cell. Science 316, 1191–1194 (2007). ... E Betzig, et al., ...

Transcription Factor Dynamics: One Molecule at a Time

Transcription factors (TFs) are key mediators of these signals, binding to specific regulatory elements within chromatin. While live-cell ...

Visualizing transcription in real-time - De Gruyter

Recent experimental efforts have attempted to visualize these processes as they take place on genes in living cells and to quantify the kinetics ...

Transcription dynamics in single cells - Netherlands Cancer Institute

We have developed a novel single-molecule imaging platform to directly visualize both transcription binding dynamics and transcriptional output in the same cell ...

LlamaTags: A Versatile Tool to Image Transcription Factor Dynamics ...

Thus, LlamaTags now make it possible to visualize the flow of information along the central dogma in live embryos. INTRODUCTION. The cells of a developing ...