Volumetric growth tracking of patient|derived cancer organoids ...

Volumetric growth tracking of patient-derived cancer organoids ...

An automated image analysis framework was developed to perform 3D single-organoid tracking of PCOs across multiple time points over 48 hours.

Volumetric growth tracking of patient-derived cancer organoids ...

This work demonstrates that OCT and 3D single-organoid tracking are attractive tools to monitor volumetric growth and drug response in PCOs.

Volumetric growth tracking of patient-derived cancer organoids ...

Metabolic inhibitors and cancer therapies decreased PCOs volumetric growth rate compared to control PCOs. Single-organoid tracking improved ...

(PDF) Volumetric growth tracking of patient-derived cancer ...

PDF | Patient-derived cancer organoids (PCOs) are in vitro organotypic models that reflect in vivo drug response, thus PCOs are an ...

Volumetric growth tracking of patient-derived cancer organoids ...

This work demonstrates that OCT and 3D single-organoid tracking are attractive tools to monitor volumetric growth and drug response in PCOs, providing rapid ...

Volumetric growth tracking of patient-derived cancer organoids ...

Metabolic inhibitors and cancer therapies decreased PCOs volumetric growth rate compared to control PCOs. Single-organoid tracking improved sensitivity to drug ...

Volumetric growth tracking of patient-derived cancer organoids ...

Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography. Biomed. Opt. Express Pub Date : 2021-06-03

Automated detection and growth tracking of 3D bio-printed organoid ...

Gil et al. (2021) used OCT to track the volumetric growth of patient-derived intestinal cancer organoids, which employed k-means clustering to segment the ...

Segmentation and Multi-Timepoint Tracking of 3D Cancer ... - MDPI

... organoid growth in patient-derived cancer organoids ... Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography.

Understanding patient-derived tumor organoid growth ... - PLOS

Einar Bjarki Gunnarsson, Seungil Kim, Brandon Choi, J. Karl Schmid, Karn Kaura, Heinz-Josef Lenz, Shannon M. Mumenthaler, Jasmine Foo.

Patient-derived tumor organoids: a new avenue for preclinical ...

However, although they are essential for the growth of colon organoids derived from healthy tissue, in most colorectal cancer cells, the ...

Quantifying the drug response of patient-derived organoid clusters ...

introduced an OCT method to track the volumetric growth of colorectal cancer PDOs, preliminarily verifying the feasibility of OCT in evaluating organoid drug ...

Comparison of Cell and Organoid-Level Analysis of Patient-Derived ...

Using dynamic confocal live cell imaging and data analysis methods we examined tumor cell growth rates and drug response behaviors in colorectal cancer (CRC) ...

Treatment-induced Changes in Patient-Derived Cancer Organoid ...

Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography. Article. Full-text available. Jun 2021. Daniel ...

Patient-derived cancer organoid tracking with wide-field one-photon ...

The ORR is sensitive to early drug-induced changes in cell metabolism that precede changes in tumor volume, proliferation (e.g., Ki67), and cell ...

Patient-derived cancer organoid tracking with widefield one-photon ...

The optical redox ratio is sensitive to early drug-induced changes in cell metabolism that precede changes in tumor volume, proliferation (e.g., ...

Druggable Growth Dependencies and Tumor Evolution Analysis in ...

established patient-derived tumor organoids (PDTOs) from neuroendocrine neoplasms including low-grade pulmonary neuroendocrine tumors. Multi- ...

Microfluidic Platform for Generating and Releasing Patient‐Derived ...

... Derived Cancer Organoids with Diverse Shapes: Insight into Shape-Dependent Tumor Growth ... volume of 300 µL per EKGel per well. Following ...

Patient-derived organoids in translational oncology and drug ...

In epithelial tumor organoids, overgrowth of normal cells will affect the growth of tumor cells. The limited tumor sample purity can confuse the ...

High-throughput Imaging of Drug Response in Tumor Organoids

... patient-derived organoids using selective plane illumination ... development and treatment planning in cancer patients. Over the ...