What Can Proteomics Tell Us About Platelets?

What can proteomics tell us about platelets? - PubMed

More than 130 years ago, it was recognized that platelets are key mediators of hemostasis. Nowadays, it is established that platelets ...

What Can Proteomics Tell Us About Platelets? | Circulation Research

Platelet proteomics will represent an invaluable tool for characterizing the fundamental processes that affect platelet homeostasis.

Full article: How can we use proteomics to learn more about platelets?

It is now apparent that the platelet proteome is comprised of thousands of different proteins, where specific changes in platelet protein ...

The Perspectives of Platelet Proteomics in Health and Disease - MDPI

On the other hand, platelet proteomics could offer a substantial biomarker-finding tool in other disorders, outside those primarily connected to platelets, ...

The first comprehensive and quantitative analysis of human platelet ...

The anucleate nature of platelets renders proteomics a valuable tool to help and better understand physiologic as well as pathophysiologic processes related ...

(PDF) What Can Proteomics Tell Us About Platelets? - ResearchGate

Recent data indicate that the platelet proteome, defined as the complete set of expressed proteins, comprises >5000 proteins and is highly similar between ...

What can the plasma proteome tell us about platelets (and vice ...

The plasma proteome can mirror the platelet proteome, and hence play an important role in elucidating both physiologic and pathologic processes.

Assessment of a complete and classified platelet proteome ... - Nature

Human genetic studies supported by mouse models show that hundreds and possibly thousands of platelet-expressed proteins contribute to ...

Platelet proteomics in cardiovascular diseases - ScienceDirect.com

Platelet proteomics can be applied to cardiovascular research to search for novel platelet biomarkers and drug targets.

Analysis of the Healthy Platelet Proteome Identifies a New Form of ...

Platelet activation induces the secretion of proteins that promote platelet aggregation and inflammation. However, detailed analysis of the released ...

What can proteomics tell us about platelets? - Abstract - Europe PMC

Modern platelet proteomics approaches can reveal (1) quantitative changes in the abundance of thousands of proteins, (2) post-translational modifications, (3) ...

What Can Proteomics Tell Us About Platelets? - Maastricht University

Modern platelet proteomics approaches can reveal (1) quantitative changes in the abundance of thousands of proteins, (2) post-translational ...

Platelet proteomics - Journal of Thrombosis and Haemostasis

Summary. As anucleate cell particles, platelets do not lend themselves to analysis by traditional cell and molecular biology techniques.

Platelet proteomic profiling reveals potential mediators of ...

Translational studies have indicated that the platelet proteome influences pathways relating to immune response, inflammation, and malignancy.7, ...

Platelet proteome reveals features of cell death, antiviral response ...

The proteomic data also point to platelet involvement in an essential cross-talk mechanism through cytokine processing and signaling pathways, ...

What can proteomics tell us about platelets? - BioSeek.eu

Modern platelet proteomics approaches can reveal (1) quantitative changes in the abundance of thousands of proteins, (2) post-translational modifications, (3) ...

Integration of Proteomics and Genomics in Platelets

The platelet transcriptome was compared with the proteome by relating both to UniGene clusters. Platelet proteomic data correlated well with the transcriptome, ...

What can the plasma proteome tell us about platelets (and vice ...

Depending on the condition, the plasma proteome can mirror the platelet proteome, and hence play an important role in elucidating both physiologic and ...

Platelet proteomics - Journal of Thrombosis and Haemostasis

Proteomics is a young field and there are only a handful of published examples applying proteomics to platelet research. This number will increase over the next ...

Molecular Proteomics and Signalling of Human Platelets in Health ...

Mass spectrometry-based proteomic techniques are contributing not only to the identification and quantification of new platelet proteins, but also reveal post- ...