White matter microstructural differences in children and genetic risk ...

Genetic risk for MS is associated with spatially distinct clusters of increased FA during childhood brain development.

Genetic risk for MS is associated with spatially distinct clusters of increased FA during childhood brain development. Keywords: Multiple sclerosis, genetic ...

White matter microstructural differences in children and genetic risk ...

Conclusion: Genetic risk for MS is associated with spatially distinct clusters of increased FA during childhood brain development.

White matter microstructural differences in children and genetic risk ...

Interpretation: This is the first study to show that greater genetic predisposition for MS is associated with higher global brain WM FA at an early age in the ...

White matter microstructural differences in children and genetic risk ...

The MS-PRS was positively associated with the number of molehills (β = 0.9, SE = 0.29, p = 0.002). Molehills were found more often in the corpus callosum (β = ...

White matter microstructural differences in children and genetic risk ...

CONCLUSION: Genetic risk for MS is associated with spatially distinct clusters of increased FA during childhood brain development. Original ...

Differences in White Matter Microstructure Among Children With ...

Findings In this cross-sectional study of 31 children with DCD and 30 children without DCD, widespread differences in indices of white matter ...

Common genetic variation influencing human white matter ... - Science

On average, common genetic variants explained 41% (standard error = 2%) of the variation in white matter microstructure. The 151 identified ...

White matter microstructure in children and adolescents with ADHD

Furthermore, white matter is particularly sensitive to remodelling with exposure to pubertal hormones (Juraska and Willing, 2017) and adolescence is a crucial ...

Aberrant White Matter Microstructure in Children with 16p11.2 ...

We therefore posit that the increased FA of 16p11.2 deletion syndrome has a different biophysical basis than an etiologically heterogeneous ASD ...

Common and heritable components of white matter microstructure ...

Individual differences in white matter (WM) microstructure have been shown to be related to cognitive functions in adults (1, 2) and children (3 ...

White matter microstructure is associated with language in children ...

While there was evidence for widespread associations between white matter microstructure and language, there was little evidence of differences in these ...

White matter microstructure in a genetically defined group at ...

Although this study is preliminary considering the small sample size, reduced white matter integrity in the corpus callosum may be a ...

Identifying neurodevelopmental anomalies of white matter ... - Nature

One of the strongest genetic risk factors for psychosis is 22q11.2 deletion syndrome (22q11.2DS), a neurogenetic developmental disorder ...

Genetic risk for Alzheimer disease in children: Evidence from early ...

IQ was measured using a well-validated Dutch nonverbal IQ test (n = 1908) at ages 5 to 9 years. White-matter microstructure was assessed by ...

White matter microstructural impairments and genetic liability to ...

Increased genetic liability for bipolar disorder was associated with reduced fractional anisotropy across distributed regions of white matter in patients and ...

White matter microstructure, traumatic brain injury, and disruptive ...

Results: Among children without TBIs, those with DBDs showed sex-specific differences in WMM of several tracts relative to TD. Most differences ...

Genetic risk for schizophrenia and developmental delay is ... - Nature

Our focus on brain structural abnormalities was based on the hypothesis that convergent mechanisms contributing to neurodevelopmental disorders ...

Brain Differences in Infants at Differential Genetic Risk for Late ...

The more limited white matter regions with a significantly stronger association between MWF and age in the ε4 carrier group are shown in orange; ...

Longer screen time utilization is associated with the polygenic risk ...

Longitudinal analyses indicate a directional effect of white matter microstructure on the ADHD scale, and a bi-directional effect between the ...