Wnt/β|catenin signalling
Wnt/β-catenin signalling: function, biological mechanisms ... - Nature
The Wnt/β-catenin signalling pathway is a key downstream molecular pathway of TGF-β-mediated myocardial fibrosis. TGF-β stimulates Wnt secretion ...
Wnt/β-catenin signaling: components, mechanisms, and diseases
Abstract. Signaling by the Wnt family of secreted glycolipoproteins via the transcription co-activator β-catenin controls embryonic development and adult ...
Wnt/beta-catenin pathway: modulating anticancer immune response
This article summarizes the role of Wnt/β-catenin pathway in cancer and ongoing therapeutic strategies involving this pathway.
Wnt signaling pathway - Wikipedia
In cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through ...
Wnt/β-catenin signaling in cancers and targeted therapies - Nature
In this study, we systematically reviewed the most updated knowledge of Wnt/β-catenin signaling in cancers and relatively targeted therapies.
Wnt Beta Catenin Pathway - Cell Signaling Technology
The conserved Wnt/β-Catenin pathway regulates stem cell pluripotency and cell fate decisions during development.
Targeting the Wnt/β-catenin signaling pathway in cancer
This scoping review aims at outlining the latest progress on the current approaches and perspectives of Wnt/β-catenin signaling pathway targeted therapy in ...
Wnt/β-Catenin Signaling Pathway | Overview, Purpose and APC ...
Lesson on the Wnt/β-Catenin signaling pathway (also known as simply the Wnt signaling pathway), including an introduction to the pathway, ...
Wnt/β-catenin signalling: function, biological mechanisms ... - PubMed
The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in embryonic development and adult tissue homeostasis.
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic ...
Here, we describe the core Wnt/β-catenin signaling pathway, how it controls stem cells, and contributes to disease. Finally, we discuss strategies for Wnt- ...
WNT/β-catenin Signaling - GeneGlobe
Wnt signaling leads to the stabilization of cytosolic β-catenin which then translocates to the nucleus and facilitates the transcription of Wnt target genes.
beta-Catenin-dependent Wnt Signaling Pathways - R&D Systems
The beta-Catenin-dependent signaling pathway is initiated by association of Wnt with the Frizzled and LRP-5/6 receptors. This association activates Dishevelled, ...
Targeting Wnt/β-Catenin Pathway for Drug Therapy - ScienceDirect
Here, we review current indications for drug therapy and some problems in the treatment process that may be addressed in future investigations.
Wnt signalling: conquering complexity | Development
Our choice to focus mainly on developmental genetics and so-called 'Wnt/β-catenin signalling' means that we had to omit many beautiful and ...
Wnt/β-Catenin Signaling in Development and Disease - Cell Press
Wnt signaling is involved in virtually every aspect of embryonic development and also controls homeostatic self-renewal in a number of adult tissues. Germline ...
Canonical Wnt / β-Catenin Signaling - Sigma-Aldrich
Wnt proteins in the stem cell niche control the behavior of various types of stem cells maintaining them in self-renewing state. The extracellular Wnt proteins ...
KEGG Wnt signaling pathway - Homo sapiens (human)
... catenin through inhibition of the bea-catenin degradation complex. Beta-catenin is then free to enter the nucleus and activate Wnt-regulated genes through ...
Wnt/β-catenin signaling promotes differentiation, not self-renewal, of ...
We demonstrate that OCT4 represses β-catenin signaling during self-renewal and that targeted knockdown of OCT4 activates β-catenin signaling in hESCs.
The Wnt/β-catenin signaling pathway - YouTube
Description: Animation showing a simplified version of the canonical Wnt/ β-catenin signaling pathway. For more information, see page 148 in ...
Wnt–β-catenin signaling: Current Biology - Cell Press
This primer provides an overview of how Wnts are released from producing cells and how they signal from the cell surface to the nucleus of receiving cells.