Wnt signaling pathway is epigenetically regulated by methylation of ...

Activation of the Wnt signaling pathway has been implicated recently in the pathogenesis of leukemia. We studied the function of epigenetic regulation of ...

Activation of the Wnt signaling pathway has been implicated recently in the pathogenesis of leukemia. We studied the function of epigenetic ...

Epigenetic alterations of the Wnt signaling pathway in cancer

One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly ...

Wnt signaling pathway is epigenetically regulated - ProQuest

Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia ... You might have access to the full article... Try ...

Epigenetic Regulation of the Wnt/β-Catenin Signaling Pathway in ...

Non-canonical Wnt signaling, consisting of Planar cell polarity (PCP) and Ca+ signaling pathways, has been shown to converge with multiple pathways and regulate ...

Epigenetic regulation of Wnt-signaling pathway in acute ...

Methylation of Wnt inhibitors was associated with activation of the Wnt-signaling pathway as demonstrated by the up-regulation of the Wnt ...

Wnt/β-catenin signalling: function, biological mechanisms ... - Nature

The canonical Wnt pathway mainly controls cell proliferation, whereas the noncanonical Wnt pathways regulate cell polarity and migration, and ...

Epigenetic regulation of the Wnt-signaling pathway in CIMP-H ...

Conclusions: Genes under methylation regulation in the BRAF-mutant context showed enrichment in Wnt-signaling pathway. Since BRAFV600E CRC tumors have a low ...

Epigenetic regulation of Wnt-signaling pathway in acute ...

Methylation of Wnt inhibitors was associated with activation of the Wnt-signaling pathway as demonstrated by the up-regulation of the Wnt ...

Epigenetic regulation of Wnt signaling pathway in urological cancer

We hypothesized that gene silencing mediated through aberrant promoter methylation of upstream Wnt antagonist genes might result in β-catenin accumulation, ...

Epigenetic Regulation of WNT Signaling Pathway Genes in ...

Methylation of the WNT signaling genes is an early event seen in patients with IBD colitis and there is a progressive increase in methylation of the WNT ...

Systematic CpG Islands Methylation Profiling of Genes in the Wnt ...

The Wnt pathway extracellular inhibitors, such as SFRPs family and WIF1, are frequently silenced by promoter hypermethylation in cancers including EOC (33, 35– ...

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in ...

Wnt/β-catenin signaling is one of the most frequently deregulated pathways in colorectal cancer and is thus an important therapeutic target. Our study ...

EHMT2 epigenetically suppresses Wnt signaling and is a potential ...

Wnt signaling is downregulated in embryonal rhabdomyosarcoma (ERMS) and contributes to the block of differentiation. Epigenetic mechanisms ...

Wnt signaling pathway is epigenetically regulated by methylation of ...

Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia ... Authors: A Valencia; J Román-Gómez; J Cervera; E ...

Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen ...

The activity of the Wnt–β-catenin signaling pathway depends primarily on the activity of glycogen synthase kinase-3 (GSK3), which plays a key ...

Targeting histone methyltransferase G9a inhibits growth and Wnt ...

Notably, APC2 is frequently inactivated by promoter methylation in lung cancer [19, 20]. Studies have demonstrated that Wnt signaling pathway ...

HERES, a lncRNA that regulates canonical and noncanonical Wnt ...

Wnt signaling pathways are often dysregulated in ESCC; however, the role of lncRNAs in such dysregulation was also undetermined. We found 6 lncRNAs that are ...

Diagnostic role of Wnt pathway gene promoter methylation in non ...

Wnt signal pathway genes are known to be involved with cancer development. Here we tested the hypothesis whether DNA methylation of genes part ...

Epigenetic regulation of the non‐canonical Wnt pathway in acute ...

Wnt signaling occurs through the canonical and non-canonical pathways. The canonical pathway has a central mediator, β-catenin. In the absence ...