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X Chromosome Inactivation


X Chromosome Inactivation | Learn Science at Scitable - Nature

A prime example of X inactivation is in the coat-color patterning of tortoiseshell or calico cats (Figure 1). In cats, the fur pigmentation gene is X-linked, ...

X-inactivation - Wikipedia

X-inactivation is a process by which one of the copies of the X chromosome is inactivated in therian female mammals. The inactive X chromosome is silenced ...

X-chromosome inactivation: the molecular basis of silencing

X-chromosome inactivation occurs randomly for one of the two X chromosomes in female cells during development. Inactivation occurs when RNA ...

Landscape of X chromosome inactivation across human tissues

Multiple transcriptome approaches, including single-cell sequencing, demonstrate that escape from X chromosome inactivation is widespread ...

X Chromosome Inactivation and Embryonic Stem Cells - NCBI

X chromosome inactivation (XCI) is a process required to equalize the dosage of X-encoded genes between female and male cells. XCI is initiated very early ...

X-inactivation (article) | Khan Academy

in Turner syndrome, a woman lacks part or all of one of her X chromosomes (leaving her with just one functional X). People with this disorder develop as females ...

X-Chromosome Inactivation and Related Diseases - PMC

X-chromosome inactivation (XCI) is the form of dosage compensation in mammalian female cells to balance X-linked gene expression levels of the two sexes.

X Inactivation and Escape: Epigenetic and Structural Features

X inactivation represents a complex multi-layer epigenetic mechanism that profoundly modifies chromatin composition and structure of one X ...

X-Inactivation - an overview | ScienceDirect Topics

Briefly, X chromosome inactivation is a process in female mammalian cells in which one copy of the X chromosome is inactivated. This ensures that females ...

X chromosome: MedlinePlus Genetics

This phenomenon is called X-inactivation or lyonization. X-inactivation ensures that people with two X chromosomes have only one functional copy ...

X chromosome inactivation in human development

ABSTRACT. X chromosome inactivation (XCI) is a key developmental process taking place in female mammals to compensate for the imbalance in the ...

Lyonization - National Human Genome Research Institute

Lyonization (also called X-inactivation) refers to the normal phenomenon in which one of the two X chromosomes in every cell of a female individual is ...

X Chromosome Inactivation - an overview | ScienceDirect Topics

X Chromosome Inactivation ... X Chromosome Inactivation refers to the process in females where one copy of the X chromosome is silenced to ensure balanced gene ...

X Inactivation - YouTube

... inactivated X chromosome. This explains why almost all calico cats are female. Intro Music Atribution Title: I4dsong_loop_main.wav Artist ...

X‐Chromosome Inactivation and Related Diseases - Sun - 2022

X-chromosome aneuploidy results in disease phenotypes in human: TS (45, X), Klinefelter syndrome (47, XXY), and triple X syndrome (47, XXX). For ...

Understanding the genetics of X chromosome inactivation

The X chromosome inactivation relies on epigenetic mechanisms. A non-coding RNA, called Xist (X-inactive specific transcript), is expressed in ...

Study challenges prior understanding of X chromosome inactivation

It was recently discovered that a unique form of X inactivation takes place during early embryonic development in humans, where XIST is expressed from both X ...

X Inactivation and Epigenetics: Vibrant Animation & Explanation

X inactivation is a type of gene dosage compensation. In humans, the sex chromosomes X and Y determine the sex of an individual – females have two X chromosomes ...

Human genes escaping X-inactivation revealed by single cell ...

The X-inactivation is an event that occurs independently for each cell. Thus, collecting expression data from single cells allows monitoring ...

X Chromosome Inactivation - iBiology

The X chromosome is many time larger than the Y chromosome. To compensate for this genetic inequality, female mammalian cells undergo X chromosome ...