a comprehensive review of biomarkers in acute kidney injury

Despite the extensive use of serum creatinine and blood urea nitrogen (BUN) levels for diagnosing acute kidney injury (AKI), these traditional ...

These biomarkers offer nuanced insights into specific facets of renal injury, aiding in differentiating prerenal and intrinsic renal injury and providing a more ...

Biomarkers in acute kidney injury – pathophysiological basis and ...

Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in the recent past. These molecules can be detected in urine or blood ...

Biomarkers in acute kidney injury | Annals of Intensive Care | Full Text

The traditional biomarkers of AKI, serum creatinine and urine output, have important limitations. The discovery of new functional and damage/stress biomarkers

Biomarkers for the Early Detection of Acute Kidney Injury - PMC

A meta-analysis of pediatric and adult studies revealed an overall AUC of 0.894 for prediction of AKI, when NGAL was measured within 6 hours after contrast ...

Biomarkers of acute kidney injury: From discovery to the future of ...

This review strives to provide a brief historical perspective on AKI, elucidate recent developments in diagnosing and managing AKI, and show the current usage ...

Persistent acute kidney injury biomarkers: A systematic review and ...

Various biomarkers reportedly predict persistent acute kidney injury (AKI) despite their varying predictive performance across clinical trials. This study ...

Recommendations on Acute Kidney Injury Biomarkers From the ...

In a meta-analysis of more than 15 000 patients, the pooled AUROCs for urine and blood NGAL for prediction of KRT were 0.72 (95% CI, 0.64-0.80) ...

A Comprehensive Review of Biomarkers in Acute Kidney Injury

These biomarkers offer nuanced insights into specific facets of renal injury, aiding in differentiating prerenal and intrinsic renal injury and providing a more ...

Biomarkers in pursuit of precision medicine for acute kidney injury

Novel biomarkers offer promise in predicting persistent AKI, with urinary motif chemokine ligand 14 displaying significant sensitivity and specificity.

Review of the limitations of current biomarkers in acute kidney injury ...

The lack of early markers of renal failure contributes significantly to the high mortality and morbidity rate associated with AKI. Due to the ...

Are biomarkers in acute kidney injury ready for prime time? The time ...

Since the early 2000s, the definition of acute kidney injury (AKI) has become sensitive and refined, but the current definition of AKI still ...

Exploring the Landscape of Biomarkers in Acute Kidney Injury - MDPI

In this review, we propose an up-to-date and comprehensive summary of advancements that identified novel biomarker candidates in blood and urine.

Biomarkers for the prediction of acute kidney injury - Oxford Academic

In this paper, we review available biomarker studies on the early predictive performance in developing AKI in adult critically ill patients.

Advances in the study of subclinical AKI biomarkers - Frontiers

Acute kidney injury (AKI) is a prevalent and serious illness in all clinical departments, with a high morbidity and death rate, particularly in intensive care ...

Full article: A long journey for acute kidney injury biomarkers

Currently, the standard diagnostic tools for AKI detection are SCr concentration and UO, both of which are markers of renal function, but not kidney injury [ ...

Acute Kidney Injury: Biomarker-Guided Diagnosis and Management

A number of studies have demonstrated that new biomarkers are more sensitive in detecting AKI in certain populations than serum creatinine and urine output ...

Acute kidney injury | Nature Reviews Disease Primers

New biomarkers to identify injury before function loss await clinical implementation. AKI and AKD are a global concern. In low-income and middle ...

Biomarkers for the diagnosis and risk stratification of acute kidney ...

Urine N-acetyl-β-D-glucosaminidase, KIM-1, and IL-18 performed the best for mortality risk prediction after AKI. In conclusion, published data from studies of ...

Acute kidney disease and acute kidney injury biomarkers in ...

This investigation confirmed that AKI biomarkers can predict AKD in CCU patients. Age, hemoglobin, ejection fraction and serum IL-18 were ...