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an alternative measure for meta‐analytic surrogate endpoint validation


an alternative measure for meta-analytic surrogate endpoint validation

In many therapeutic areas, the identification and validation of surrogate endpoints is of prime interest to reduce the duration and/or size of clinical ...

Surrogate threshold effect: an alternative measure for meta‐analytic ...

In many therapeutic areas, the identification and validation of surrogate endpoints is of prime interest to reduce the duration and/or size ...

18 An Alternative Measure for Meta-analytic Surrogate Endpoint ...

When considering the meta-analytic approach to the validation of surrogate endpoints (Chapter 7), Gail et al. (2000) noted that, unless the trial-level.

An Alternative Measure for Meta-analytic Surrogate Endpoint ...

'An Alternative Measure for Meta-analytic Surrogate Endpoint Validation' published in 'The Evaluation of Surrogate Endpoints'

an alternative measure for meta‐analytic surrogate endpoint validation

A new concept is introduced, the so‐called surrogate threshold effect (STE), defined as the minimum treatment effect on the surrogate necessary to predict a ...

An alternative measure for meta-analytic surrogate endpoint validation

Overall survival and progression-free survival curves for the meta-analysis of advanced ovarian cancer. Surrogate threshold effect 175.

An alternative measure for meta-analytic surrogate endpoint validation

... Surrogate threshold effect (STE) is defined as the minimum treatment effect on the surrogate endpoint necessary to predict a nonzero ...

An alternative trial-level measure for evaluating failure-time ...

To validate a failure-time surrogate for an established failure-time clinical endpoint such as overall survival, the meta-analytic approach is commonly used ...

An Alternative Measure for Meta-analytic Surrogate Endpoint ...

Request PDF | On Mar 30, 2006, Tomasz Burzykowski and others published An Alternative Measure for Meta-analytic Surrogate Endpoint Validation | Find, ...

an alternative measure for meta‐analytic surrogate endpoint ...

10.1002/pst.207.abs. In many therapeutic areas, the identification and validation of surrogate endpoints is of prime interest to reduce the duration and/or ...

Statistical validation of surrogate outcome measures - PubMed Central

The validation of surrogate endpoints in meta-analyses ... Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation.

The validation of surrogate endpoints in meta-analyses of ...

The two measures of association, one at the individual level, the other at the trial level, are proposed as an alternative way to assess the usefulness of a ...

[PDF] The validation of surrogate endpoints in meta-analyses of ...

Surrogate threshold effect: an alternative measure for meta‐analytic surrogate endpoint validation · T. BurzykowskiM. Buyse. Medicine. Pharmaceutical statistics.

The meta-analytic framework for the evaluation of surrogate ...

The validation of surrogate endpoints in meta-analyses ... Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation ...

The Strength of Association Between Surrogate End Points and ...

Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation. Pharm Stat. 2006;5(3):173-186.PubMed ...

Systematic Review and Recommendation for Reporting of Surrogate ...

... clinical endpoints through meta-analytic ... M. Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation.

Surrogate threshold effect: an alternative measure for meta-analytic ...

Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation. Burzykowski, T.; Buyse, M. Pharmaceutical Statistics 5(3): ...

Correlation between surrogate endpoints and overall survival in ...

& Buyse, M. Surrogate threshold effect: An alternative measure for meta-analytic surrogate endpoint validation. Pharm. Stat. 5, 173–186. https ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID ...

... surrogate-endpoint validation that use a meta-analytic ... Surrogate threshold effect: An alternative measure for meta-analytic surrogate endpoint validation.

Surrogate endpoints in oncology: when are they acceptable for ...

Surrogate threshold effect: an alternative measure for meta-analytic surrogate endpoint validation. Pharm Stat. 2006;5:173–86. Article ...