improved predictions of MHC antigen presentation by ...

improved predictions of MHC antigen presentation by ... - PubMed

We here present NetMHCpan-4.1 and NetMHCIIpan-4.0, two web servers created to predict binding between peptides and MHC-I and MHC-II, respectively.

NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of ...

In both cases, the binding between MHC and antigenic peptides is the most selective step in the antigen presentation pathway. Therefore, the ...

Improved Prediction of MHC II Antigen Presentation through ...

We apply the NNAlign_MA machine learning framework to analyze and integrate large-scale eluted MHC II ligand mass spectrometry (MS) data sets to advance ...

Improved Prediction of MHC II Antigen Presentation ... - PubMed

Major histocompatibility complex II (MHC II) molecules play a vital role in the onset and control of cellular immunity.

NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of ...

In both cases, the binding between MHC and antigenic peptides is the most selective step in the antigen presentation pathway. Therefore, the prediction of ...

Improved predictions of antigen presentation and TCR recognition ...

This process requires epitopes to be presented on class I human leukocyte antigen (HLA-I) molecules and recognized by the T-cell receptor (TCR).

Improved predictions of antigen presentation and TCR recognition ...

MHCflurry 2.0: improved pan-allele prediction of MHC class I-presented peptides by incorporating antigen processing. Cell Syst. 11. 42–48.e7 ...

Improved prediction of MHC II antigen presentation through ...

In a highly selective process, MHC II presents peptides derived from exogenous antigens on the surface of antigen-presenting cells for T cell ...

NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of ...

Improved prediction of MHC II antigen presentation through integration and motif deconvolution of mass spectrometry MHC eluted ligand data · Biology, Medicine.

NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of ...

In both cases, the binding between MHC and antigenic peptides is the most selective step in the antigen presentation pathway. Therefore, the prediction of ...

Improved Prediction of MHC II Antigen Presentation through ...

Major histocompatibility complex class II (MHC II) molecules play a pivotal role in the adaptive immune system. Antigen- presenting cells (APCs) ...

Improving MHC class I antigen-processing predictions using ...

In this work, we propose a new deep-learning model, MHCrank, to predict the probability that a peptide will be processed for presentation by MHC class I ...

[PDF] Improved prediction of MHC II antigen presentation through ...

This work integrates data from eluted MHC ligand mass spectrometry assays that inherently contains signals of the events leading to antigen presentation, ...

NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of ...

In both cases, the binding between MHC and antigenic peptides is the most selective step in the antigen presentation pathway. Therefore, the prediction of ...

Improved prediction of MHC II antigen presentation through ...

Major Histocompatibility Complex II (MHC II) molecules play a key role in the onset and control of cellular immunity. In a highly selective ...

Improved prediction of HLA antigen presentation hotspots ...

Advancements in mass spectrometry (MS) technologies have greatly enhanced the sensitivity of MHC-associated peptide proteomics (MAPPs) assays.

Improved prediction of MHC-peptide binding using protein language ...

Major histocompatibility complex Class I (MHC-I) molecules bind to peptides derived from intracellular antigens and present them on the surface of cells, ...

The journey towards complete and accurate prediction of HLA ...

Jonas Birkelund Nilsson and Morten Nielsen are co-authors on the paper “Accurate prediction of HLA class II antigen presentation across all loci using tailored ...

MHCflurry 2.0: Improved Pan-Allele Prediction of MHC Class I ...

Considering only peptides first predicted by the binding model to bind strongly to MHC, the antigen processing model is trained to discriminate ...

Predicting Antigen Presentation—What Could We Learn From a ...

Antigen presentation lies at the heart of immune recognition of infected or malignant cells. For this reason, important efforts have been made to predict which ...