miR|34c|5p functions as pronociceptive microRNA in cancer pain by ...

miR-34c-5p functions as pronociceptive microRNA in cancer pain by ...

These results show that Cav2.3 is a novel mechanistic target for a key pronociceptive miRNA, miR-34c-5p, in the context of cancer pain.

miR-34c-5p functions as pronociceptive microRNA in cancer pain by ...

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels. Jagadeesh Gandla1, 2, Santosh Kumar Lomada1 ...

(PDF) MiR-34c-5p functions as pronociceptive microRNA in cancer ...

microRNAs are a class of non-coding RNAs with emerging functional importance in chronic pain. In a genome-wide screen for microRNAs regulated in dorsal root ...

miR-34c-5p functions as pronociceptive microRNA in cancer pain by ...

microRNAs (miRNAs) are a class of noncoding RNAs with emerging functional importance in chronic pain. In a genome-wide screen for miRNAs regulated in dorsal ...

MicroRNA Biology and Pain - ScienceDirect.com

2018, Pain Medicine (United States). MiR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels. 2017, Pain ...

Microrna 34c | Sigma-Aldrich

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels. Jagadeesh Gandla et al. Pain ...

The Regulatory Mechanisms and Therapeutic Potential of MicroRNAs

miRNAs also directly targeted proinflammatory cytokines mRNAs to modulate neuropathic pain behaviors. A significant reduction in miR-142-3p expression was ...

Down‐regulation of microRNA‐34c‐5p alleviates neuropathic pain ...

This study aimed to test the hypothesis that miR-34c-5p can modulate neuropathic pain in rat models with chronic constriction injury (CCI) of sciatic nerve.

The Role of miRNAs in Neuropathic Pain - MDPI

Overexpression of miR-144 reverses nerve injury-induced mechanical allodynia and thermal hyperalgesia and leads to a reduction in pro-inflammatory cytokines in ...

MicroRNA‐34c‐5p Inhibition of NUF2 Suppresses Lung ...

MicroRNAs (miRs) are key regulators of gene expression and show their oncogenic or antioncogenic role in human cancers including lung cancer. In ...

Down‐regulation of microRNA‐34c‐5p alleviates neuropathic pain ...

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels · Biology, Medicine. Pain · 2017.

Genome‐wide identification and functional analyses of microRNA ...

Further detailed analyses will reveal which of these putative targets mediate the pronociceptive functions of miR‐34c‐5p and miR‐370‐3p in the context of cancer ...

MicroRNA-based therapy in pain medicine: Current progress and ...

In a model of spinal nerve ligation, expression of miRNAs-96, miR-182, and miR-183 are downregulated in ipsilateral dorsal root ganglia (DRG) in rats. The ...

MiR-135-5p alleviates bone cancer pain by regulating astrocyte ...

Bone cancer pain (BCP) was associated with microRNA dysregulation. In this study, we intended to clarify the potential role of miR-135-5p in a ...

Mirnas That Predispose to Neuropathic Pain Identified Using ...

... microRNA signatures associated with cancer pain. EMBO Mol Med 2013, 5 ... miR-34c-5p functions as pronociceptive microRNA in cancer pain by targ... Go ...

Role of Micro-RNA for Pain After Surgery - DigitalCommons@TMC

miR-34c-5p functions as pronociceptive. microRNA in cancer pain by targeting Cav2.3 containing calcium channels. Pain. 2017;158:1765–1779. [PubMed: 28614186].

Analyses of cellular expression of miR-34c-5p in dorsal root ganglia ...

Spinal microRNAs might contribute to the development of BCP and the role of microglial activation is controversial. In this study, we established a BCP model by ...

MiR-34a is differentially expressed in dorsal root ganglia in a rat ...

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels · J. GandlaS. LomadaJianning LuR. KunerK. Bali.

The role of micro-RNAs in neuropathic pain—a scoping review

At a molecular level, microRNAs (miRNAs) act as regulators of gene expression orchestrating both immune and neuronal processes. Thus, miRNAs may act as ...

MicroRNA-34c-5p Inhibition of NUF2 Suppresses Lung ...

MicroRNAs (miRs) are key regulators of gene expression and show their oncogenic or antioncogenic role in human cancers including lung cancer. In ...