miR‑34c‑5p targets Notch1 and suppresses the metastasis and ...

The present study concluded that miR‐34c‐5p was a tumor suppressor in CC and may be a novel measure for the future treatment of CC.

miR-34c-5p targets Notch1 and suppresses the metastasis and ...

In gastric cancer, miR-34c-5p was revealed to directly bind to the 3′UTR of the microtubule-associated protein tau (MAPT) and inhibit the ...

miR‑34c‑5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer. Authors: Huali Wei; Xiaolan Wang; Xiumin Niu; Ruili ...

miR-34c-5p targets Notch1 and suppresses the - ProQuest

miR-34c-5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer. Wei, Huali; Wang, Xiaolan; Niu, Xiumin; Jiao, Ruili; Li, Xiaojuan ...

miRNA 34c Suppresses Osteosarcoma Progression In Vivo by ...

Mechanistically, we confirmed that miR 34c directly targets the 3′ untranslated region (3′UTR) of multiple components of Notch signaling (Notch1, Notch2, and ...

Up-regulation of miR-34c-5p inhibits nasopharyngeal carcinoma ...

MiR-34c-5p targets NOTCH1. It was found that ... MiR-34c suppresses tumor growth and metastasis in nasopharyngeal carcinoma by targeting MET.

MicroRNA-34c-3p target inhibiting NOTCH1 suppresses ...

We combined clinical and experimental studies to establish the role of microRNA (miR)-34c in NSCLC metastasis and chemoresistance. Results. MiR-34c expression ...

Notch1 is a target of miR-34c-5p. (A) The 3'-UTR of Notch1 mRNA...

Luciferase activity was analyzed after 24 h of transfection. (C) mRNA expression levels of Notch1 were determined in HeLa cells (D and E) The protein expression ...

miR-34c-5p inhibited fibroblast proliferation, differentiation and ...

A dual-luciferase reporter assay confirmed that miR-34c-5p can target MDMX rather than Notch1. ... 34c‑5p Targets Notch1 And Suppresses The ...

miR-34c-5p mediates the cellular malignant behaviors of oral ...

miR-34c-5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer. Mol Med Rep 2021;23:120. [Crossref] [PubMed]; Li N ...

The role of miR-34c-5p/Notch in epithelial-mesenchymal transition ...

Dual luciferase gene reporter assays revealed that miR-34c-5p specifically targets Notch1 3 'UTR, and Western blot analyses showed that miR-34c-5p promotes ...

MicroRNA-34c-3p target inhibiting NOTCH1 suppresses ...

MiR-34c-3p suppresses the proliferation and invasion of non-small cell lung cancer (NSCLC) by inhibiting PAC1/MAPK pathway.

MicroRNA-34 Family in Cancers: Role, Mechanism, and Therapeutic ...

Similarly, miR-34c exerts suppressive effects on metastasis ... miR-34c-5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer.

Differential effects of miR‑34c‑3p and miR‑34c‑5p on the ...

The proliferation inhibition effect of miR-34c-5p ... miR‑34c‑5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer ...

MiR-34c-3p targets Notch2 to inhibit cell invasion and ... - SciELO

Change in Invasion Capacity of NPC Cell Lines Measured by Transwell. 3.6 Overexpression of miR-34c-5p suppressed the EMT markers. As shown in Figure 6A, the ...

Up-regulation of miR-34c-5p inhibits nasopharyngeal carcinoma ...

Abstract Objective: To explore the correlation between miR-34c-5p and NOTCH1 in nasopharyngeal carcinoma (NPC). Materials and methods: qPCR was employed to ...

MiR-34c downregulation leads to SOX4 overexpression and ...

MiR-34c was downregulated in NPC patient samples, and confirmed in vitro to directly target SOX4, a master regulator of epithelial-to- ...

MiR-137 inhibits cervical cancer progression via down-modulating ...

miR-34c-5p targets Notch1 and suppresses the metastasis and invasion of cervical cancer. Mol Med Rep 2021;23:120. [Crossref] [PubMed]; Xu J, Wu G, Zhao Y, et ...

MiR-34a-5p promotes multi-chemoresistance of osteosarcoma ...

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in ... MicroRNA-34a suppresses invasion through downregulation of Notch1 ...

p53/miR-34 axis in development and disease - Oxford Academic

Ectopic expression of miR-34a or miR-34c in these cells reduces self-renewal and inhibited EMT via silencing its target genes Bcl2 and Notch1−4. Interestingly, ...