microRNA|34c is a novel target to treat dementias

microRNA-34c is a novel target to treat dementias - PMC - NCBI

A patent application for targeting miR-34c to treat memory impairment is pending. The European Neuroscience Institute is jointly funded by the Max Planck ...

microRNA-34c is a novel target to treat dementias - PubMed

MicroRNAs are key regulators of transcriptome plasticity and have been implicated with the pathogenesis of brain diseases.

microRNA‐34c is a novel target to treat dementias | The EMBO Journal

Using integrative genetics, we identify miR‐34c as a negative constraint of memory consolidation and show that miR‐34c levels are elevated in the hippocampus of ...

MicroRNA-34c is a novel target to treat dementias - ResearchGate

Using integrative genetics, we identify miR-34c as a negative constraint of memory consolidation and show that miR-34c levels are elevated in the hippocampus of ...

Increased microRNA-34c abundance in Alzheimer's disease ...

Repression of expression of selected candidate target genes of miR-34a and miR-34c by transfection analysis. ... microRNA-34c is a novel target to treat dementias ...

The role of microRNA-34 family in Alzheimer's disease: A potential ...

Zovoilis et al. microRNA‐34c is a novel target to treat dementias. EMBO J. (2011). S. Sarkar et al. Over-expression of miR-34a induces rapid cognitive ...

MicroRNA-34c Downregulation Ameliorates Amyloid-β-Induced ...

Therefore, focusing on Aβ-targeted miRNAs may have therapeutic implications for AD. We found that miR-34c, a miRNA that was previously reported ...

MicroRNAs: pioneering regulators in Alzheimer's disease ... - Nature

... new therapeutic targets and provide new ideas for intervention strategies in Alzheimer's disease. [miR microRNA, APP amyloid precursor ...

The Role of microRNAs in Alzheimer's Disease and Their ... - MDPI

Comprehensive understandings of the expression profiles and activities of these miRNAs will illuminate their roles as potential therapeutic targets in AD brain ...

MicroRNAs in Alzheimer's disease: Potential diagnostic markers and ...

Every three seconds, a new case of dementia is diagnosed worldwide. There is currently no effective treatment for most forms of dementia, but therapy and ...

miRNA-34c Overexpression Causes Dendritic Loss and Memory ...

miR-124 expression in the medial prefrontal cortex could partially rescue the behavioral deficits associated with frontotemporal dementia [6].

Neurodegeneration and Aging: Could MicroRNA Be the Link?

microRNA-34c is a novel target to treat dementias. EMBO J. 2011 Oct 19;30(20):4299-308. PubMed. Further Reading. Papers. Cogswell JP, Ward J ...

The emerging role of microRNAs in Alzheimer's disease - Frontiers

Interestingly, miRNA-9, miRNA-125b, miRNA-146a, miRNA-155 are also ... microRNA-34c is a novel target to treat dementias. EMBO J. 30, 4299–4308 ...

microRNA-34c is a novel target to treat dementias. - KP Bibliotek

microRNA-34c is a novel target to treat dementias.-article.

Plasma microRNA vary in association with the progression of ...

... novel therapeutic targets for the treatment of dementia. Several recent meta-analyses have sought to identify a consensus microRNA signature ...

Potential microRNA-related targets in clearance pathways of ...

Understanding of the mechanism of microRNA in the associated signal pathways could identify novel therapeutic targets for the treatment of AD.

MicroRNAs influence and longevity

... MiR-30a: a novel biomarker and potential therapeutic target for cancer. ... microRNA-34c is a novel target to treat dementias. EMBO J 30(20): ...

MicroRNA Biomarkers in Neurodegenerative Diseases and ...

MicroRNA-34c is a novel target to treat dementias. EMBO J 2011;30:4299–4308.ArticlePubMedPMC; 71. Kim J, Yoon H, Ramírez CM, Lee SM, Hoe HS ...

A microRNA signature that correlates with cognition and is a target ...

In conclusion, these data further confirm the hypothesis that increased levels of the 3 microRNAs reflect key processes important to neuronal ...

MicroRNA-195Protects Against Dementia Induced by Chronic Brain ...

7C) and the percentage of swimming distance in the target quadrant relative to the total distance in 2VO rats (⬃38%) compared with 2VO rats treated by NC. (Fig.