- of Genetically Engineered CAR|T Cells Using Bifunctional Small ...🔍
- Redirection of genetically engineered CAR|T cells using bifunctional ...🔍
- Redirection of Genetically Engineered CAR|T Cells Using ...🔍
- of Genetically Engineered CAR‑T Cells Using Bifunctional Small ...🔍
- Engineering strategies to overcome the current roadblocks in CAR T ...🔍
- A new insight in chimeric antigen receptor|engineered T cells for ...🔍
- Bifunctional αHER2/CD3 RNA|engineered CART|like human T cells ...🔍
- Making Potent CAR T Cells Using Genetic Engineering and ...🔍
of Genetically Engineered CAR|T Cells Using Bifunctional Small ...
of Genetically Engineered CAR-T Cells Using Bifunctional Small ...
We demonstrate that a bifunctional small molecule “switch” consisting of folate conjugated to fluorescein isothiocyanate (folate-FITC) can redirect and ...
Redirection of genetically engineered CAR-T cells using bifunctional ...
Chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) provide a potent antitumor response and have become a promising treatment option ...
(PDF) Redirection of Genetically Engineered CAR-T Cells Using ...
Herein, we demonstrate that a bifunctional small molecule "switch" consisting of folate conjugated to fluorescein isothiocyanate (folate-FITC) ...
Redirection of genetically engineered CAR-T cells using bifunctional ...
It is demonstrated that a bifunctional small molecule "switch" consisting of folate conjugated to fluorescein isothiocyanate (folate-FITC) can redirect and ...
Redirection of genetically engineered CAR-T cells using bifunctional ...
Chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) provide a potent antitumor response and have become a promising treatment option for cancer.
Redirection of Genetically Engineered CAR-T Cells Using ... - Scite
Mentioning: 129 - Chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) provide a potent antitumor response and have become a promising treatment ...
of Genetically Engineered CAR‑T Cells Using Bifunctional Small ...
Chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) provide a potent antitumor response and have become a promising treatment option for cancer.
Engineering strategies to overcome the current roadblocks in CAR T ...
T cells genetically engineered to express chimeric antigen receptors (CARs) have proven — and impressive — therapeutic activity in patients ...
A new insight in chimeric antigen receptor-engineered T cells for ...
Adoptive cell therapy using chimeric antigen receptor (CAR)-engineered T cells has emerged as a very promising approach to combating cancer.
Bifunctional αHER2/CD3 RNA-engineered CART-like human T cells ...
The chimeric antigen receptor-expressing T cell (CART) approach has achieved success in clinical trials of patients with non-solid tumors. Some ...
Making Potent CAR T Cells Using Genetic Engineering and ...
Chimeric antigen receptor (CAR)-engineered T cells have shown dramatic clinical results in patients with hematological malignancies. However, it is still ...
CAR-cell therapy in the era of solid tumor treatment
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a promising immunotherapeutic approach to fight cancers.
Emerging Approaches for Regulation and Control of CAR T Cells
Chimeric antigen receptor (CAR) T cells have emerged as a promising treatment for patients with advanced B-cell cancers. However, widespread application of ...
Recent Advances in Allogeneic CAR-T Cells - MDPI
T cells were engineered to have the ability to attack tumor cells by generating CAR constructs consisting of genes encoding scFv, a co-stimulatory domain (CD28 ...
Remote controlling of CAR-T cells and toxicity management
The therapeutic activity of the on-switch CAR-T cell requires a small priming molecule in addition to the cognate antigen, and neither small molecule nor ...
Versatile strategy for controlling the specificity and activity of ... - PNAS
The adoptive transfer of autologous T cells engineered to express a chimeric antigen receptor (CAR) has emerged as a promising cancer therapy. Despite ...
CAR T Cells: Engineering Immune Cells to Treat Cancer - NCI
In a small clinical trial of adults with lymphoma, for example, patients treated with a “remodeled” CD-19-targeted CAR T cell developed at NCI ...
CAR-T cells for Colorectal Cancer: Target-selection and strategies ...
The design of “switch” mediated CARs through small molecules that control the therapeutic effect of T cells while still retaining antigen specificity, may make ...
Editorial: Translation of genetically engineered T cells in cancer ...
Genetically engineered T cells have made tremendous contributions to cancer immunotherapy. Chimeric antigen receptor (CAR)-modified T cells have demonstrated ...
In biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor ...