validation of surrogate endpoints in advanced solid tumours

Validation of surrogate endpoints in advanced solid tumors - PubMed

We review current statistical approaches to surrogate-endpoint validation based on meta-analysis in various advanced-tumor settings.

Validation of Surrogate Endpoints in Advanced Solid Tumours

Validation of Surrogate Endpoints in Advanced Solid Tumours: Systematic Review of Statistical Methods, Results, and Implications for Policy Makers. O. Ciani.

validation-of-surrogate-endpoints-in-advanced-solid-tumors ...

Methods: We review current statistical approaches to surrogate-endpoint validation based on meta-analysis in various advanced-tumor settings. We assessed the ...

Validation of Surrogate Endpoints in Advanced Solid Tumors

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID. TUMOURS: SYSTEMATIC REVIEW OF STATISTICAL METHODS,. RESULTS, AND IMPLICATIONS FOR POLICY-MAKERS. Address ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID TUMORS: SYSTEMATIC REVIEW OF STATISTICAL METHODS, RESULTS, AND IMPLICATIONS FOR POLICY MAKERS - Volume ...

Validation of Surrogate Endpoints in Advanced Solid Tumors

This is a repository copy of Validation of Surrogate Endpoints in Advanced Solid Tumors: Systematic Review of Statistical Methods, Results, and Implications ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID TUMORS: SYSTEMATIC REVIEW OF STATISTICAL METHODS, RESULTS, AND IMPLICATIONS FOR POLICY MAKERS. Ciani ...

CL3 – Validation of Surrogate Endpoints in Advanced Solid ...

Request PDF | CL3 – Validation of Surrogate Endpoints in Advanced Solid Tumours: Systematic Review of Statistical Methods, Results, and Implications for ...

Review of meta-analyses evaluating surrogate endpoints for overall ...

Meta-analyses have been widely used for the validation of surrogate endpoints, specifically in oncology. ... endpoints and OS for multiple advanced solid-tumor ...

VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID ...

Methods: We review current statistical approaches to surrogate-endpoint validation based on meta-analysis in various advanced-tumor settings. We assessed the ...

Review of Surrogate Endpoint Validation Methodologies and ...

required to validate surrogate endpoints for use in solid tumour HTAs. PRM10 ... METHODS: We searched phase II and phase. III clinical trials of advanced breast ...

Evaluating the evidence behind the surrogate measures included in ...

... surrogate endpoints for solid tumors listed in the FDA Table of Surrogate Endpoints. ... surrogate endpoint in advanced breast cancer. Int J ...

Validation of surrogate endpoints in advanced solid tumours ...

Request PDF | On Jan 1, 2014, O. Ciani published Validation of surrogate endpoints in advanced solid tumours: Systematic review of statistical methods, ...

Validation of progression-free survival (PFS) as surrogate endpoint ...

Validation of progression-free survival (PFS) as surrogate endpoint in randomised trials of immune checkpoint inhibitors in advanced solid cancers · Abstract.

Frequently asked questions on surrogate endpoints in oncology ...

... surrogate endpoints used in trials of advanced cancers. However, in ... solid tumours – perspectives from clinical trials and clinical practice.

Validation of progression-free survival (PFS) as surrogate endpoint ...

... surrogate endpoint in randomised trials of immune checkpoint inhibitors in advanced solid cancers ... Submitted abstracts Immunotherapy of cancer 1278P Validation ...

The Strength of Association Between Surrogate End Points and ...

Accessed May 12, 2015. 33. Ciani O, Davis S, Tappenden P, et al. Validation of surrogate endpoints in advanced solid tumors: systematic ...

Table of Surrogate Endpoints That Were the Basis of Drug Approval ...

Patients with advanced prostate cancer ... solid tumors; cholangiocarcinoma; bladder cancer; neuroblastoma; mismatch repair deficient solid tumors

FDA validation of surrogate endpoints in oncology: 2005–2022

The number of cancer drugs approved based on surrogate endpoints is rising. ... advanced breast cancer in 2010 [7]. However, the drug remained on the US ...

validation of surrogate endpoints in advanced solid tumors ... - OUCI

Authors: Oriana Ciani; Sarah Davis; Paul Tappenden; Ruth Garside; Ken Stein; Anna Cantrell; Everardo D. Saad; Marc Buyse; Rod S. Taylor. Abstract.