1 Clinical and biological insights from viral genome sequencing 1 2 ...

Viral genome sequencing methods: benefits and pitfalls of current ...

The viral genome is the predominant site of intracellular host-viral interactions. Understanding the viral genome provides valuable insights ...

From Clinical Specimen to Whole Genome Sequencing of A(H3N2 ...

(1) Background: Over the last few years, there has been growing interest in the whole genome sequencing (WGS) of rapidly mutating pathogens, ...

1 Introduction | Genomic Epidemiology Data Infrastructure Needs for ...

When combined with epidemiological information, genomic sequencing can be particularly useful for investigating outbreaks of RNA viruses, such as SARS-CoV-2.

Viral Surveillance Panel | For SARS-COV-2, flu, polio ... - Illumina

Whole-genome sequencing and characterization of >200 viruses and ... sequencing, providing insight to viral evolution and broad viral surveillance.

Direct genome sequencing of respiratory viruses from low viral load ...

The Twist Comprehensive Viral Research Panel contains probes derived from 8,050 strains of influenza A viruses and only one strain of SARS-CoV-2 ...

Comparison of Herpes Simplex Virus 1 Strains Circulating in Finland ...

Importantly, the phylogenetic clusters were not predictive of any detectable pattern in phenotypic differences, demonstrating that whole-genome relatedness is ...

Center for Pathogen Genomics and Microbial Evolution

As these technologies have become more affordable, easier to use and widely available, there has been an explosion of genomic sequence generated with hundreds ...

What is viral whole-genome sequencing - FutureLearn

Depending on the size of the viral genome, multiple multiplex (i.e. more than one primer pair in the reaction) PCR reactions will be used to amplify the genome, ...

Combination of long- and short-read sequencing fully resolves ...

We performed further analysis to determine whether the four possible HSV-2 isomeric genomes were present in the sequenced viral population. We ...

DNA sequencing - Wikipedia

The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has ...

practical_guide_week1

A size comparison of viral genomes and major groups of living organisms. Source Pearson Education · Click to enlarge the image · Download Figure 1 and 2 alt- ...

The application of long-read sequencing in clinical settings

Long-read DNA sequencing technologies have been rapidly evolving in recent years, and their ability to assess large and complex regions of ...

Deep-sequencing of viral genomes from a large and diverse cohort ...

We analysed deep-sequenced viral genomes from 2,650 treatment-naive HIV-infected persons to measure the intrahost genetic diversity of 2,447 ...

Four milestones powering the genome sequencing revolution - UKRI

1. Discovering the structure of DNA · 2. Developing DNA sequencing · 3. Next generation sequencing for cheaper, faster genome data · 4. Portable ...

Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA ...

It makes WGS easier and faster with long-read assembly. In this study, we obtained WGS of two strains of ZIKV following the established protocol ...

Genomic diversity of SARS-CoV-2 during early introduction into the ...

The analyses described above rely on complete and accurate SARS-CoV-2 sequences. We used a tiled amplicon sequencing approach on the Oxford Nanopore platform to ...

Efficient Algorithms for Large Scale Analysis of Viral Genome ...

Backward mutations are not allowed, recurrent mutations are allowed. 1: Initialize a tree rooted at reference, and a queue of all sequences. 2: ...

Application of next-generation sequencing to identify different ...

NGS can be used to detect several infections. In contrast to conventional sequencing techniques, which allowed for the sequencing of one or a few very short DNA ...

Optimisation and evaluation of viral genomic sequencing of SARS ...

Sequencing of SARS-CoV-2 from rapid diagnostic tests (RDTs) can bolster viral genomic surveillance efforts; however, approaches to maximise ...

Human Genome Project Fact Sheet

Ultimately, the project used one particular method for DNA sequencing, called Sanger DNA ... How did the Human Genome Project affect biological ...