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Adoptive transfer of EBV|specific T cells results in sustained clinical ...


Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1 ...

Adoptive ex vivo transfer of EBNA-1-specific T cells is a feasible and well-tolerated therapeutic option, representing a fast and efficient procedure to ...

(PDF) Adoptive Transfer of Epstein-Barr Virus (EBV) Nuclear ...

RESULTS: We report on the use of adoptive transfer of EBNA-1-specific T cells in 10 pediatric and adult patients with EBV viremia and/or PTLD ...

Adoptive transfer of allogeneic Epstein–Barr virus (EBV)

EBV-specific immunity, as well as T-cell repertoire in the tumor, before and after immunotherapy, was evaluated. Results: CTL transfer was well tolerated, and a ...

The interplay between Epstein-Barr virus and the immune system

Immunotherapy of EBV-related malignancies, together with melanoma, can be regarded as a paradigmatic example of the potential use of adoptive T-cell therapy.88 ...

Epstein-Barr virus–specific human T lymphocytes expressing ...

We now report that EBV-specific (but not primary) T cells transduced with tumor-specific chimeric receptor genes can be expanded and maintained long-term.

Strategies of adoptive T -cell transfer to treat refractory viral ...

Adoptive transfer of virus-specific T cells is an attractive approach to restore protective T -cell immunity in patients with refractory viral infections after ...

Adoptive T cell therapy as treatment for Epstein Barr Virus

Although vaccination resulted in an increased number of tumor-reactive T-cells in the majority of cases, clinical responses were induced only sporadically.2 ...

Activation and adoptive transfer of Epstein–Barr virus-specific ...

These results demonstrate that a potent EBV-specific memory response can be expanded from solid organ recipients who have acquired their primary EBV infection ...

A single exercise bout enhances the manufacture of viral-specific T ...

The adoptive transfer of donor-derived viral-specific cytotoxic T-cells (VSTs) is an effective treatment for controlling CMV and EBV infections ...

Adoptive transfer of EBV-specific T cells in patients with ... - YouTube

Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS characterized by progressive demyelination and disability.

Rejection resistant CD30.CAR-modified Epstein-Barr virus-specific T ...

CAR. Hence, they could proliferate extensively and maintained function both through their native EBV-specific T cell receptor and the CD30.CAR. The CD30.CAR ...

Cytotoxic T Cell Adoptive Immunotherapy as a Treatment for ...

2010. Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J. Immunother.

Adoptive Transfer of EBV-specific T Cells Results in ... - Altmetric

Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma.

Pathogen-specific T Cells: Targeting Old Enemies and New...

Feucht et al showed that adoptive transfer of TH1 cells is a safe and effective alternative therapeutic approach for refractory AdV disease or viremia after HCT ...

Virus-Specific T Cells: Broadening Applicability

These deficiencies in conventional therapeutics have increased interest in an immunotherapeutic approach to viral disorders, leading to adoptive transfer of ...

Adoptive T cell therapy as treatment for Epstein Barr Virus

Homing, persistence and tumor-protective effects of adoptive- ly transferred EBV-specific T-cells have previously been demonstrated for highly immuno- genic EBV ...

Adoptive Immunotherapy with Antigen-Specific T Cells Expressing a ...

Several groups have reported activity with autologous EBV-specific T-cell treatment, but more studies now focus on third-party EBV-specific T ...

Safety and clinical efficacy of rapidly-generated trivirus-directed T ...

Adoptive transfer of virus-specific T cells can prevent and treat serious infections with Epstein-Barr virus (EBV), cyto- megalovirus (CMV), and adenovirus ...

Adoptive Immunotherapy for Cancer or Viruses - Annual Reviews

Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J ...

fiBarr virus-specific cytotoxic T cells in solid organ transplant ...

Adoptive Transfer of CTL and Clinical Monitoring. For adoptive transfer, CTL lines were subsequently tested for microbial contamination and were prepared for ...