Association of circulating tumor DNA with patient prognosis in ...

Clinical Utility of Tumor-Naïve Presurgical Circulating Tumor DNA ...

Presurgical ctDNA detection was observed in 55 of 414 patients (13%) with clinical stage I lung adenocarcinoma (LUAD) and was associated with poor recurrence- ...

Association of circulating tumor DNA dynamics with clinical ...

... Furthermore, direct evidence of chemotherapy activity in this population is ctDNA clearance in 34 of 39 (87%) patients [5]. Similar high ...

Circulating tumor DNA for predicting recurrence in patients with ...

In this meta-analysis, ctDNA detection was associated with an increased risk of BC recurrence and death. •. The association with worse outcomes ...

Circulating tumor DNA in advanced solid tumors: Clinical relevance ...

Genomic profiling traditionally uses tumor tissue derived from surgical resection or biopsy specimens and primarily focuses on identifying ...

Association Between Circulating Tumor DNA and Survival in ...

The detection of ctDNA at the time of metastatic breast cancer diagnosis is a poor prognostic factor and could potentially be used as a ...

Circulating tumor DNA monitoring for early recurrence detection in ...

These results suggest that monitoring ctDNA could be beneficial in clinical decision-making for EOC patients. Keywords. Epithelial ovarian ...

Clinical significance and biology of circulating tumor DNA in high ...

Conversely, ctDNA negativity after NAC correlates with improved outcomes, even in patients with extensive residual cancer. Pretreatment tumor ...

Monitoring response to neoadjuvant chemotherapy in triple negative ...

Baseline ctDNA was detected in 90% (27/30) of patients, of whom 70.4% (19/27) achieved ctDNA clearance by mid-NAC. ctDNA clearance at mid-NAC ...

Association Between Circulating Tumor DNA and Recurrence-Free ...

Association Between Circulating Tumor DNA and Recurrence-Free Survival in Patients with Resected Stage III Melanoma · Fill form to unlock content.

Circulating tumor DNA to guide diagnosis and treatment of localized ...

As a result of the improvement in the techniques for DNA analysis, above all next-generation sequencing (NGS) assays, circulating tumor DNA (ctDNA) has become ...

Targeted genotyping of circulating tumor DNA for classical Hodgkin ...

Mean of DeltaSUVmax after C2 was -78.8%. We analyzed ctDNA after C2 for 54 patients (90%). ctDNA became rapidly undetectable in all cases after C2. Variant ...

Relationship of tumor fraction in circulating tumor DNA with ...

Circulating tumor DNA (ctDNA) is a promising prognostic biomarker and emerging evidence shows that a single time point/measurement of ctDNA ...

Circulating tumor DNA in cancer diagnosis, monitoring, and prognosis

ctDNA has clinical applications in disease diagnosis and monitoring. Some studies succeed in identifying mutations in a patient's tumor by using ...

Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma

We found an association between high metabolic tumor burden and the detection of somatic variants in ctDNA in patients with locally advanced ...

Evidence for the Utility of ctDNA Monitoring for Recurrence After

In updated analysis with 2240 patients and 23 month median follow-up, the study researchers demonstrate that ctDNA-based molecular residual ...

Medical Policy Manual - Circulating Tumor DNA and ... - Bynder

Symonds (2020) examined the association between a positive Colvera® test result and recurrence of colorectal cancer in 144 patients who had no evidence of ...

Circulating tumor DNA clearance predicts prognosis across ...

Circulating tumor DNA (ctDNA), validated as a tool for mutation detection in lung cancer, could reflect dynamic molecular changes. We evaluated the utility of ...

Circulating tumor DNA and radiological tumor volume identify ...

Therefore, we hypothesized that detection of circulating tumor DNA (ctDNA) can identify patients with increased risk of relapse and that ...

GALAXY Trial: Circulating Tumor DNA Appears Prognostic in ...

Patients who tested positive for ctDNA 4 weeks after surgery had an 11- to 13-times increased risk for recurrence. The analysis of ctDNA ...

Circulating Tumor DNA Analysis in Patients With Cancer - Allen Press

All ctDNA assays have an appreciable rate of discordance with tumor testing, and the ctDNA assay may not detect the variant observed in the ...