B|cell lymphoma 2

BCL2 mutations are associated with increased risk of transformation ...

Other B-cell lymphomas and normal controls. To assess the frequency of BCL2 mutations in other lymphoma subtypes, DNA was isolated from 39 DLBCLs, 117 mucosa- ...

BCL2 Expression Is a Prognostic Marker for the Activated B-Cell ...

2. Alizadeh AA, Eisen MB, Davis RE, et al: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403::503,2000- ...

A novel Bcl-2 inhibitor, BM-1197, induces apoptosis ... - BMC Cancer

Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy in adults, accounting for 30–40% of all non-Hodgkin's lymphoma (NHL) ...

B-cell lymphoma protein - Proteopedia, life in 3D

Bcl-2 is a family of genes and proteins that govern the mitochondrial membrane permeabilization (MMP).

Specific interactions of BCL-2 family proteins mediate sensitivity to ...

(A-D) The importance of the anti-apoptotic proteins BCL-XL (A, C) and MCL-1 (B, D) in diffuse large B-cell lymphoma (DLBCL) was confirmed using ...

BCL2 - B-cell CLL/lymphoma 2 - WikiGenes

BCL2 - B-cell CLL/lymphoma 2. Homo sapiens. Synonyms: Apoptosis regulator Bcl-2, Bcl-2, PPP1R50. Chao, D.T. et al., Gauwerky, C.E. et al., Katoh, O. et al ...

B-cell lymphoma 2 (Bcl-2) protein family - Aladdin Scientific

Aladdin Scientific specializes in producing top-tier B-cell lymphoma 2 (Bcl-2) protein family, and more. Trusted by the global R&D ...

BCL-2 family isoforms in apoptosis and cancer | Cell Death & Disease

Following the initial discovery of BCL-2 in the context of B-cell lymphoma in the 1980s, a number of homologous proteins have since been ...

Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2 ...

This study demonstrates a new approach to target Bcl-2 using a small molecule, BFC1103, to suppress metastatic disease.

Pathobiology of follicular lymphoma - UpToDate

(See "Overview of the pathobiology of the non-Hodgkin lymphomas", section on 'B cell lymphoma'.) ... BCL-2 is an oncogene that blocks programmed ...

B-cell lymphoma 2 (Bcl-2) – phase I clinical candidate - Vernalis

A novel, orally bioavailable, Bcl-2 selective and potent inhibitor called S55746 (also known as BCL201), which occupies the hydrophobic groove of Bcl-2, was ...

BCL-2 Proteins in Pathogenesis and Therapy of B-Cell Non ... - MDPI

The ability to inhibit mitochondrial apoptosis is a hallmark of B-cell non-Hodgkin lymphomas (B-NHL). Activation of mitochondrial apoptosis is tightly ...

Diffuse large B cell lymphoma (DLBCL) - Cancer Research UK

It contains a high number of white blood cells (lymphocytes) which fight infection. Diagram of the lymphatic system. There are two types of lymphocytes: T ...

B-Cell Lymphoma: Outlook, Treatment, Types, and More - Healthline

This is part of your immune system, which is responsible for fighting off bacteria, viruses, and other foreign bodies. There are two types of ...

Double hit lymphoma - The Leukaemia Foundation

DHL is an uncommon subtype of diffuse large B-cell lymphoma (DLBCL), making up about 5% of DLBCL cases.

diffuse large B-cell lymphoma (DLBCL) - Lymphoma Action

Lymphocytes are part of your immune system. They travel around your body in your lymphatic system, and help you fight infections and cancers. There are two ...

Double-Hit Lymphoma in DLBCL: Symptoms, Survival Rate, and More

Some medical scientists classify DHL as high-grade B-cell lymphoma. Read on to learn about what causes double-hit lymphoma, how it's treated, and the survival ...

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B ...

Patients with diffuse large B-cell lymphoma that is refractory to primary and second-line therapies or that has relapsed after stem-cell ...

B-cell Lymphoma - MD Anderson Cancer Center

B-cell lymphomas are the most common type of non-Hodgkin lymphoma. About 85% of all lymphomas in the United States are considered B-cell.

Types of T-cell Lymphoma - American Cancer Society

What Is Non-Hodgkin Lymphoma? Types of B-cell Lymphoma ... Anaplastic large cell lymphoma (ALCL): About 2% of lymphomas are of this type.