Cellular fate of a plant virus immunotherapy candidate

Reconceptualizing Cancer Immunotherapy Based on Plant ...

The use of nanoparticle technology based on plant viruses as a novel strategy to target and combat cancers is also included. The review concludes with a ...

Recombinant helical plant virus-based nanoparticles for vaccination ...

Thus, chimeric BVP1 virions expressing a partial sequence of VP1 protected target animals by generating humoral and cell-mediated immune ...

Identification of Plant Virus Receptor Candidates in the Stylets of ...

Because noncirculative viruses are acquired when plant sap or cell contents are pumped through the stylets and released when saliva is spitted out, their ...

Oncolytic Virotherapy: A New Paradigm in Cancer Immunotherapy

Most viral vectors initiate immunogenic cell death (ICD) by releasing tumor-associated antigens, which are followed by antitumor immune responses. By activating ...

Harnessing adenovirus in cancer immunotherapy: evoking cellular ...

Recombinant adenovirus (rAd) represents an attractive candidate for virus vaccination and cancer immunotherapy. For viral vaccination, rAd can ...

Cell Fate Reprogramming in the Era of Cancer Immunotherapy

Tumor cells frequently accumulate mutations in pathways securing cellular anti-viral defense, rendering themselves vulnerable to viral infections. This cancer ...

Cancer immunotherapy candidate provokes powerful dual response ...

They found that inhibiting PTPN2 and PTPN1 in tumor cells made the cells more susceptible to certain cell-killing signals produced by immune ...

In situ vaccination with cowpea mosaic virus elicits systemic ...

Results ISV with CPMV induces systemic antitumor T-cell-mediated immunity that inhibits growth of untreated tumors and requires conventional type-1 dendritic ...

Cancer chemotherapy and beyond: Current status, drug candidates ...

The future of cancer immunotherapy: microenvironment-targeting combinations ... Advancing oncolytic virus therapy by understanding the biology. Nat Rev Clin ...

Turnstone Biologics - Leading the Fight Against Solid Tumors

Turnstone Biologics is committed to bringing the next generation of viral immunotherapies to cancer patients. Learn about our science and pipeline.

Nicole Steinmetz - UCSD Profiles

Cellular fate of a plant virus immunotherapy candidate. Commun Biol. 2024 Oct 24; 7(1):1382. Omole AO, Affonso de Oliveira JF, Sutorus L, Karan S, Zhao Z ...

Emergex T Cell-Priming Vaccine Candidate for Betacoronaviruses ...

... cell-priming Betacoronavirus candidate. NIAID is projected to cover ... Emergex has a growing proprietary pipeline of innovative immunotherapy ...

Vault, viral, and virus-like nanoparticles for targeted cancer therapy

Such plant virus-based nanocarriers have been deemed as promising candidates to reduce the effective dosage of anticancer drugs (like ...

Effector-mediated plant–virus–vector interactions - Oxford Academic

Another major immune mechanism used by plants is RNA silencing. Plants recognize double-stranded RNA derived from virus genomes and produce small interfering ...

A therapy candidate for fatal prion diseases turns off ... - Broad Institute

Delivering genes into the human brain is challenging; many clinical trials have used adeno-associated viruses (AAVs) as gene-delivery vehicles, ...

Viral therapy for targeted drug delivery to cancers - ScienceDirect.com

Some animal viruses possess natural oncolytic abilities such as inducing cell apoptosis, necrosis/necroptosis, and pyroptosis via a series of immune responses.

New treatment for COVID-19 is made from plants | ASU News

Viruses, including SARS-CoV-2, use an extensive arsenal to help them cleverly evade the immune system, proliferate and cause disease.

Emerging Potential of Plant Virus Nanoparticles (PVNPs) in ...

Cancer immunotherapies using plant virus nanoparticles (PVNPs) have achieved considerable success in preclinical studies. PVNP based nanoplatforms can be ...

Future of cancer immunotherapy using plant virus-based nanoparticles

Cancer is a disease of uncontrolled cell growth and results in the spread of abnormal cells [1]. Although the human immune system is capable of ...

Candel Therapeutics Sets Path to Success: Recent Achievements ...

... Cellular Immunotherapies to identify how viral immunotherapy could enhance the efficacy of CAR-T cell therapy in solid tumors. The enLIGHTEN ...