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Cisplatin|induced nephrotoxicity in childhood cancer


Risk factors for cisplatin‐induced long‐term nephrotoxicity in ...

Although CPL-induced long-term nephrotoxicity was found in half of the pediatric CS of solid tumors, clinically significant nephrotoxicity was ...

Nephrotoxicity of Cancer Treatment in Children - Page 6 - Medscape

The clinical consequences of cisplatin nephrotoxicity include ARF, CRF and more commonly hypomagnesemia, which may cause paresthesia, tremor, tetany and ...

Chart Review of Predisposing Factors to Cisplatin-Induced ...

Cisplatin-induced nephrotoxicity is a major dose-limiting adverse event associated with the drug that can occur despite preventive measures. According to Miller ...

Hypertension in long-term childhood cancer survivors after treatment ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: relevance of age and dose as risk ...

Cisplatin-induced nephrotoxicity in childhood cancer - Ebsco

Discover this 2023 paper in Pediatric nephrology (Berlin, Germany) by Zazuli, Zulfan; Op 't Hoog, Catharina J P; Vijverberg, Susanne J H; et. al.

Cisplatin-induced nephrotoxicity in childhood cancer - OUCI

Cisplatin-induced nephrotoxicity in childhood cancer: comparison between two countries ... Authors: Zulfan Zazuli; Catharina J. P. Op 't Hoog; Susanne J. H. ...

Cisplatin nephrotoxicity aggravated by cardiovascular disease and ...

Ageing lung cancer patients may be at increased risk of Cisplatin (Cp) nephrotoxicity, because of comorbidities leading to accelerated ageing of the kidneys ...

Cisplatin Nephrotoxicity in Children Treated for Cancer - ProQuest

Cisplatin, a chemotherapy commonly used to treat pediatric solid tumours, causes acute kidney injury (AKI) and may lead to chronic kidney disease (CKD) and ...

Cisplatin-Associated Nephrotoxic Effects in Children - ResearchGate

Cisplatin-Associated Nephrotoxic Effects in Children ... Content may be subject to copyright. ... based chemotherapy and are often prohibitive of ...

Nephrotoxicity in childhood cancer survivors - VU Research Portal

Cisplatin was associated with magnesium loss and a cumulative dose > 500 mg/m2 with potassium and phosphate loss. Carboplatin cumulative dose > ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or ...

Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: relevance of age and dose as risk factors. · 117 ...

Nephrotoxicity of Cancer Treatment in Children: Pediatric Health

The cytotoxic drugs most likely to cause important chronic nephrotoxicity are ifosfamide and cisplatin, both of which are used widely in many ...

Molecular mechanisms of cisplatin-induced nephrotoxicity

However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute kidney injury (AKI) which develop due to ...

Look for nephrotoxicity in adult survivors of childhood cancer

LAS VEGAS – Adult survivors of childhood cancer treated with high-dose cisplatin or high-dose ifosfamide are at markedly increased risk for ...

Cisplatin dose rate as a risk factor for nephrotoxicity in children.

Nephrotoxicity was less severe in children who received cisplatin courses at a dose rate of 40 mg m(-2) day(-1) than in those who received higher dose rates (P ...

An exploratory analysis of cisplatin-induced nephrotoxicity and ...

Several reports have demonstrated that most patients receiving cisplatin for prolonged treatment or on high doses will develop nephrotoxicity and ototoxicty.

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

Despite its benefit in cancer therapy, cisplatin is also known for its adverse reactions, such as ototoxicity, neurotoxicity, emesis and nephrotoxicity (Percie ...

Cisplatin-induced Nephrotoxicty and its Predisposing Factors for ...

Risk factors of nephrotoxicity includes age above 50, hypertension, and NSAID while hypertension and female gender are risk factor for not recover above 75% ...

The Dutch Childhood Cancer Survivor Study (DCCSS)-LATER 2 ...

The following risk factors were investigated (yes/no): cisplatin, carboplatin, ifosfamide, HD cyclophosphamide, abdominal radiotherapy, TBI, ...

Prediction of Nephrotoxicity Associated With Cisplatin-Based ...

Cisplatin-based chemotherapy may induce nephrotoxicity. This study presents a random forest predictive model that identifies testicular cancer ...