Controlling seizures in newborns with hemimegalencephaly

Inducing strokes to better treat babies with hemimegalencephaly

... hemimegalencephaly (HME) which causes uncontrollable and frequent seizures. Dr. Monica Pearl, neurointerventional radiologist, and the team ...

Hemihypertrophy Associated with Hemimegalencephaly in a Newborn

The outcome depends, to a large extent, on the degree of seizure control that can be achieved in a child. Severe cases often have poor prognosis, with high ...

Postoperative seizure and developmental outcomes of children with ...

For children with HMEG, the predicted probability of being seizure-free three years after surgery was 79.4%.

HEMIMEGALENCEPHALY - EpilepsyDiagnosis.org

Seizure onset is typically in the first year of life, often in the neonatal period. Developmental, cognitive and motor impairments are frequent and significant ...

Hemimegalencephaly and epilepsy: an overview - SciELO

Modifications are frequently proposed by surgeons but the main objective of surgery is seizure control and reduce medications allowing the child to regain ...

Similar brain spect findings in subclinical and clinical seizures in two neonates with hemimegalencephaly ... The current therapeutic approach to seizure control ...

The history behind the novel hemimegalencephaly procedure

... seizures. Dr. Monica Pearl, neurointerventional radiologist, and Dr ... Inducing strokes to better treat babies with hemimegalencephaly.

Staged hemispheric embolization: How to treat ... - MDEdge

The abnormal hemisphere causes seizures, and when they become intractable, the standard of care is to remove it as soon as possible; the longer ...

Hemispherotomy in an infant with hemimegalencephaly - Lippincott

Hemispheric disconnection has been reported to be efficient in seizure control and prevents further cognitive injury and developmental delay.

Hemimegalencephaly (HME) - MedLink Neurology

Epilepsy, which develops in nearly all children with hemimegalencephaly, is typically refractory to medical management (124; 112) and resective or cerebral ...

Hemimegalencephaly and intractable seizures associated with the ...

Hemispherectomy is usually necessary to provide effective seizure control. The exact etiology of HME is not fully understood, but involves a disturbance in ...

Functional Hemispherectomy for Hemimegalencephaly in an Infant

Early intervention for refractory epilepsy is key to prevent sequelae of seizures, including SUDEP, neurodevelopmental decline and epileptic encephalopathy ...

Hemimegalencephaly (Chapter 44) - The Causes of Epilepsy

Seizure control is the primary goal of management in most children with hemimegalencephaly. ... seizures in two neonates with hemimegalencephaly. Pediatr ...

HEMIMEGALENCEPHALY - EpilepsyDiagnosis.org

Developmental and cognitive impairments are more common in this group. If these seizure types are seen, achieving full seizure control is important, if this is ...

Hemimegalencephaly - Wikipedia

It causes severe seizures, which are often frequent and hard to control. A minority might have seizure control with medicines, but most will need removal or ...

Journal of Pediatric Neurosciences

Initial treatment with antiepileptic drugs (AEDs) was successful in controlling her seizures ... Hemimegalencephaly: Seizure Outcome in an Infant after ...

Investigation of seizures in infants - Epilepsy Society

Phenobarbitone and phenytoin are the usual first-line drugs, but ideally only in the acute situation where early seizure-control is required. The metabolism of ...

Hemispherotomy in the First Days of Life to Treat Drug-Resistant ...

Results: The infant was diagnosed with drug-resistant lesional epilepsy due to hemimegalencephaly affecting the left hemisphere. Given congruent ...

Hemispherotomy in Infants with Hemimegalencephaly: Long-Term ...

Despite the excellent post-surgical seizure outcome, the long-term developmental outcome is quite variable between patients, ranging from mild ...

Deep Brain Stimulation in Hemimegalencephaly with Medically ...

While there is no cure, the goal is to reduce seizures with ASMs or hemispherectomy in refractive pediatric cases. Given the absence of motor deficits ...