Dexmedetomidine vs Midazolam or Propofol for Sedation During ...

Efficacy of dexmedetomidine compared with midazolam for sedation ...

The sedative benefits of dexmedetomidine vs midazolam remain inconclusive. While some secondary outcomes showed clinical effectiveness of dexmedetomidine, more ...

Pro-Con Perspective: Dexmedetomidine vs Midazolam for Sedating…

It achieved levels of sedation comparable to one of our standard agents while causing less delirium and decreasing the duration of mechanical ventilation. Aside ...

Dexmedetomidine versus midazolam/propofol sedation reduces ...

Others symptoms included MV dura- tion length of ICU and/or in-hospital stay, opioid drugs requirement, mortality and hemodynam- ic changes among patients were ...

Brain protective effect of dexmedetomidine vs propofol for sedation ...

Dexmedetomidine demonstrated stronger protective effects on the brain compared to propofol for long-term mechanical ventilation in patients ...

Dexmedetomidine vs midazolam or pr - H1 Connect

The results of these two studies suggest that dexmedetomidine is not inferior to propofol or midazolam for the long-term sedation of mechanically ventilated ...

Effects of dexmedetomidine versus propofol on outcomes in critically ...

Data on 107 and 2318 patients in DEX and propofol groups, respectively, were analyzed. Compared to the propofol group, the DEX group exhibited longer ventilator ...

Dexmedetomidine vs midazolam for sedation of critically ill patients

At comparable sedation levels, dexmedetomidine-treated patients spent less time on the ventilator, experienced less delirium, and developed less tachycardia ...

Dexmedetomidine: A Review of Its Use for Sedation in the Intensive ...

Patients receiving dexmedetomidine were also easier to rouse, more co-operative and better able to communicate than patients receiving midazolam ...

Dexmedetomidine vs. Propofol as the Primary Agent for Sedation in ...

Another trial with more patients compared dexmedetomidine to propofol or midazolam. Dexmedetomidine was non-inferior to comparators in ...

Comparison between propofol and dexmedetomidine on depth of

[10] Compared with propofol and midazolam, dexmedetomidine was as effective in maintaining adequate sedation for prolonged mechanical ventilation.[11] ...

Dexmedetomidine: its use in intensive care medicine and anaesthesia

compared dexmedetomidine for the sedation of intubated patients with the established sedatives, propofol (PRODEX) and midazolam (MIDEX). Dexmedetomidine was ...

[PDF] Dexmedetomidine versus propofol/midazolam for long-term ...

This pilot study suggests that in long-term sedation, DEX is comparable to SC in maintaining sedation targets of RASS 0 to −3 but not suitable for deep ...

The MENDS2 Trial: Dexmedetomidine vs Propofol for Sedation

Discussion: · Doses of dexmedetomidine and propofol that were used were TINY (median dose 0.27ug/kg/hr and 10ug/kg/min) · 38% of patients in the ...

Comparison of dexmedetomidine and propofol in mechanically ...

Historically, benzodiazepines and propofol were the preferred sedatives in the intensive care unit (ICU), but dexmedetomidine has recently had increased usage.

Comparative analysis of dexmedetomidine, midazolam and propofol ...

Abstract. Background: Sedation in intensive care patients is assumed to reduce discomfort from care interventions, increase.

Dexmedetomidine versus midazolam and propofol for sedation in ...

Mortality was decreased in dexmedetomidine group compared with midazolam group (OR 15.25; 95% CI, 5.29–64.80, P<0.001) and propofol group (OR 5.51; 95% CI, 1.91 ...

A Comparison of Dexmedetomidine Versus Propofol for Use in ...

... dexmedetomidine for sedation during ... sedation combination of midazolam, fentanyl and propofol for sedation during third molar surgery.

Comparison of Dexmedetomidine, midazolam and propofol for ...

One of the key factors for good clinical practice in the ICU is to provide adequate sedation. An ideal sedative should provide a rapid onset, a ...

Dexmedetomidine versus standard care sedation with propofol or ...

Dexmedetomidine was shown in two European randomized double-blind double-dummy trials (PRODEX and MIDEX) to be non-inferior to propofol and ...

Outcomes When Using Adjunct Dexmedetomidine with Propofol ...

Propensity matching resulted in 143 pair cohorts. Interventions: Dexmedetomidine with propofol or propofol alone. Measurements and Main Results: There was no ...