Estimating genetic nurture with summary statistics of ...

Estimation of Parental Effects Using Polygenic Scores

The occurrence of genetic nurture has important implications for understanding complex trait genetics. Genetic nurture increases the phenotypic ...

Genetic Nature or Genetic Nurture? Quantifying Bias in Analyses ...

Summary statistics from a genome-wide association study (GWAS) can be used ... This bias is in opposite directions; while naive OLS estimates are biased upwards, ...

Towards a deeper understanding of nature and nurture: combining ...

In such a scenario, estimates of the direct genetic effects of child genotype on child phenotype will be biased unless the indirect genetic ...

Estimating effects of parents' cognitive and non-cognitive skills on ...

data, genetic associations estimated for adoptees and non-adopted ... Genetic nurture effects on education: a systematic review and meta-analysis.

Polygenic risk scores: effect estimation and model optimization

We introduce several methods that jointly model summary statistics from multiple GWASs in genetic risk prediction. ... (2020) Estimating genetic nurture with.

Assessing the contribution of genetic nurture to refractive error - OUCI

Advances in molecular genetics now make it possible to quantify an individual's genetic predisposition to a trait via his or her 'polygenic score'. However, ...

The estimation of environmental and genetic parental influences

Although most genetically informed designs are unable to detect it, genetic nurture is a lurking presence that can bias genetic and ...

Request Data - The International Externalizing Consortium

Project: This project will use the externalizing GWAS summary statistics to calculate polygenic risk scores in other data sets. ... summary statistics and genetic ...

A TEST OF GENETIC NURTURE John Cawley Euna Han Jiyoon K

A meta-analysis by Branigan, McCallum, and Freese (2013) estimates that the heritability of educational attainment is roughly 40%. Of course, there is variation ...

GWAS deems parents guilty by association - GitHub Pages

Published under the PNAS license. See companion article, “Estimating genetic nurture with summary statistics of multigenerational genome-wide ...

Genetic nurture versus genetic transmission of risk for ADHD traits in ...

Polygenic scores are individual-level scores that summarize common variant genetic risk for a given phenotype. The scores are calculated as the ...

Twin studies to GWAS: there and back again

It began by using twin/ family studies to estimate the relative importance of genetic and environmental influences. As large-scale genotyping ...

Using parent‐offspring pairs and trios to estimate indirect genetic ...

We investigated indirect genetic effects (IGEs), also known as genetic nurture, in education with a novel approach that uses phased data to include parent- ...

fine-tuning polygenic risk scores with GWAS summary statistics

where xTy is the observed p ×1 summary statistics for N individuals and p genetic ... Estimating genetic nurture with summary statistics of multigenerational ...

Heritability v5 - Gusev Lab

○ A brief tour of methods for analyzing population structure in genetic data: ... “Estimating Genetic Nurture with Summary · Statistics of Multigenerational ...

DONUTS: Decomposing nature and nurture using GWAS ... - GitHub

DONUTS (Decomposing nature and nurture using GWAS summary statistics) is a novel statistic framework that can estimate direct and indirect genetic effects at ...

Genetic nature or genetic nurture? Introducing social genetic ...

... Gene-environment correlations can inflate the estimation of cogPGS on phenotypes 33,51, 52 . Therefore, we conducted a post hoc sibling analysis ( ...

Estimating vertical transmission and genetic nurture using polygenic ...

Estimating vertical transmission and genetic nurture using polygenic scores with Jared Balbona. 113 views · 1 year ago ...more ...

Genome-Wide Heritability Estimates for Family Life Course Complexity

We estimate the genetic contribution to sequence complexity and a wide range of family demographic behaviors using genomic relatedness–based, restricted ...

Decomposing heritability and genetic covariance by direct ... - PLOS

Estimation of heritability and genetic covariance is crucial for quantifying and understanding complex trait genetic architecture and is ...