Ferroptosis
Ferroptosis (Inhibitors Agonists Modulators Antagonists)
Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a ...
Ferroptosis (WP4313) - Homo sapiens - WikiPathways
Share this pathway ... Ferroptosis is a type of programmed cell death which is distinct from apoptosis and necrosis, since cell death occurs due to failure of the ...
Ferroptosis: Biology and Role in Gastrointestinal Disease
Ferroptosis appears to have dual roles whereby inhibition of ferroptosis can alleviate intestinal damage, whereas induction of ferroptosis has been shown to ...
Mechanisms and pharmacological applications of ferroptosis
Ferroptosis is a recently discovered form of cell death that involves small molecule-induced oxidative cell death.
Ferroptosis: the vulnerability within a cancer monster - JCI
In this issue of the JCI, Wang and colleagues examined how RB1 loss may sensitize cancer cells to ferroptosis inducers through elevation of ACSL4.
A guide to ferroptosis, the biological rust of cellular membranes
Ferroptosis is defined as an iron-catalyzed form of regulated necrosis that occurs through excessive peroxidation of polyunsaturated fatty ...
Exploring Ferroptosis-Inducing Therapies for Cancer Treatment
Ferroptosis-inducing therapies hold promise for overcoming resistance encountered with conventional treatments. However, challenges, including the lack of ...
KEGG PATHWAY: Ferroptosis - Homo sapiens (human)
KEGG Ferroptosis - Homo sapiens (human). [ Pathway menu | Organism menu | Pathway entry | Show description | Download ...
Ferroptosis in infection, inflammation, and immunity
This review focuses on new discoveries related to how ferroptotic cells and their spilled contents shape innate and adaptive immunity in health and disease.
Ferroptosis: A Hidden Cell Death Pathway I Basic Science Series
0:00 Introduction 1:00 Ferropotosis 1:30 Iron Dependant Enzyme System 1:52 Balance maintained by enzymes 2:28 Significance 2:58 Uses 3:30 ...
The role of ferroptosis in human diseases | Proteintech Group
Ferroptosis has been shown to have both pro-tumor and anti-tumor effects. It can contribute to tumor growth by promoting the death of immune cells that would ...
Mechanism of Ferroptosis: A Potential Target for Cardiovascular ...
Ferroptosis is a form of programmed cell death caused by production of reactive oxygen species and disequilibrium of iron homeostasis.
Ferroptosis as a target for protection against cardiomyopathy - PNAS
In this study, we demonstrate that ferroptosis, a newly defined iron-dependent cell death, mediates both chemotherapy- and ischemia/reperfusion- ...
Ferroptosis in Cancer Cell Biology - MDPI
A major hallmark of cancer is successful evasion of regulated forms of cell death. Ferroptosis is a recently discovered type of regulated necrosis which, ...
What is Ferroptosis? - CUSABIO
Ferroptosis is a new type of cell death that is discovered by Stockwell in 2012. It is usually accompanied by a large amount of iron accumulation and lipid ...
Ferroptosis in plants: triggers, proposed mechanisms, and the role of ...
Ferroptosis is induced upon heat and biotic stress. Fig. 1. Proposed model for ferroptosis in plants. Ferroptosis is induced upon heat ...
Blood stem cells are susceptible to ferroptosis, a type of cell death
A study of a rare bone marrow disorder reveals that even healthy stem cells are vulnerable to iron-induced cell death.
The Ferroptosis Pathway - Rockland Immunochemicals
One of them, named ferroptosis, was first described in 2012 as a nonapoptotic, iron-dependent form of cell death.
Ferroptosis Guide DOJINDO LABORATORIES
Ferroptosis is a form of programmed cell death that is caused by iron ion-dependent accumulation of lipid peroxides. Ferroptosis has been shown to follow a ...
Nutritional and Metabolic Control of Ferroptosis - Annual Reviews
Ferroptosis is a type of regulated cell death characterized by an excessive lipid peroxidation of cellular membranes caused by the ...