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Ferroptosis


Ferroptosis: past, present and future | Cell Death & Disease - Nature

Ferroptosis is a new type of cell death that was discovered in recent years and is usually accompanied by a large amount of iron ...

Ferroptosis: mechanisms and links with diseases - Nature

Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis, autophagy, and other forms of cell death.

Ferroptosis in cancer therapy: a novel approach to reversing drug ...

Ferroptosis is an intracellular iron-dependent form of cell death that is distinct from apoptosis, necrosis, and autophagy.

Ferroptosis - Wikipedia

Ferroptosis ... Oxytosis/ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is ...

Ferroptosis - an overview | ScienceDirect Topics

Ferroptosis is a form of cell death which is morphologically, biochemically and genetically distinct from apoptosis, necrosis and autophagy.

Ferroptosis - an overview | ScienceDirect Topics

Ferroptosis is a type of cell death characterized by iron-dependent phospholipid peroxidation and reactive oxygen species overproduction.

Targeting ferroptosis for cancer therapy: exploring novel strategies ...

Emerging evidence suggests ferroptosis as a potential target for cancer therapy and ferroptosis inducers including small molecules and nanomaterials have been ...

Ferroptosis turns 10: Emerging mechanisms, physiological functions ...

Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified as a distinct phe-.

Ferroptosis, radiotherapy, and combination therapeutic strategies

In this review, we summarize known as well as putative mechanisms underlying the crosstalk between radiotherapy and ferroptosis.

Ferroptosis, a new form of cell death: opportunities and challenges ...

Unlike autophagy and apoptosis, ferroptosis is an iron-dependent and reactive oxygen species (ROS)-reliant cell death with characteristics ...

The Hallmarks of Ferroptosis - Annual Reviews

Ferroptosis is a nonapoptotic, iron-dependent form of cell death that can be activated in cancer cells by natural stimuli and synthetic ...

Ferroptosis: an iron-dependent form of nonapoptotic cell death

Nonapoptotic forms of cell death may facilitate the selective elimination of some tumor cells or be activated in specific pathological ...

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism ...

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

Ferroptosis: Mechanism and connections with cutaneous diseases

Ferroptosis is a recognized novel form of programmed cell death pathway, featuring abnormalities in iron metabolism, SystemXc − /glutathione axis, and lipid ...

Ferroptosis | News & Announcements - Cayman Chemical

Ferroptosis—a previously unknown form of controlled cell death with significant similarities to oxytosis*—was described in 2012. This lethal event does not ...

Characteristics and Biomarkers of Ferroptosis - Frontiers

Ferroptosis is a non-apoptotic and oxidative damage-related RCD (Dixon et al., 2012), mainly driven by iron accumulation, lipid peroxidation, and subsequent ...

Ferroptosis Research Solutions | Thermo Fisher Scientific - US

Ferroptosis is an iron-dependent process and iron accumulation leads to reduced glutathione peroxidase activity and increased lipid peroxidation through the ...

What is the role of ferroptosis in cancer?

Recent studies reveal that ferroptosis plays a significant role in tumor suppression, giving us new opportunities for cancer treatment.

Signaling pathways and defense mechanisms of ferroptosis - Liu

In this review, we summarize recent progress in understanding the signaling pathways and defense mechanisms of ferroptosis.

Ferroptosis (Inhibitors Agonists Modulators Antagonists)

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a ...