Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

The genomic landscape of teenage and young adult T

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science. 2008;322(5906):1377- 1380. 31. Gutierrez A, Sanda ...

2978 The Relapse Mechanisms and Genomic Landscape ... - Abstract

Acute Lymphoblastic Leukemias: Biomarkers, Molecular Markers and ... acute myeloid leukemia (AML) are not completely understood. We ...

Relapsed Acute Lymphoblastic Leukemia (ALL)

Relapsed Acute Lymphoblastic Leukemia (ALL): Mutational Landscape. Multi ... The European Genome-phenome Archive (EGA) is part of the ELIXIR infrastructure.

The genomic landscape of teenage and young adult T

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science. 2008;322(5906):1377- 1380. 31. Gutierrez A, Sanda ...

Mutational landscape, clonal evolution patterns, and role of RAS ...

Relapsed acute lymphoblastic leukemia (ALL) is associated with chemotherapy resistance and poor prognosis. This study analyzes the emergence ...

Genomic landscape of B-other acute lymphoblastic leukemia in an ...

Both P2RY8-CRLF2 non-BCR-ABL1-like patients in our cohort had a favorable disease course with complete molecular response and no relapse. Herold et al. reported ...

Therapy-induced mutations drive the genomic landscape of ... - OUCI

Li and colleagues report the genomic landscape of over 100 patients with relapsed acute lymphoblastic leukemia. Analysis of diagnosis-relapse-remission ...

Mutational landscape in relapsed pediatric acute lymphoblastic ...

Relapse of acute lymphoblastic leukemia (ALL) remains a leading cause of childhood cancer-related death. Prior studies have shown clonal ...

Pediatric acute lymphoblastic leukemia - Haematologica

Therapyinduced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. Blood. 2020; 135(1):41-55. https://doi.org ...

The evolving genomic landscape of ALL: molecular genetics ...

The genomic analysis of acute lymphoblastic leukemia (ALL) is providing novel insights into the disease, which will inform and direct ...

The Current Genomic and Molecular Landscape of Philadelphia-like ...

Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk B-cell Acute Lymphoblastic Leukemia (B-ALL) characterized by a gene expression ...

The genomic landscape of high hype - H1 Connect

This letter from Nature Genetics focuses on genetic changes in high hyperdiploid acute lymphoblastic leukemia (ALL). Whole genome sequencing and/or whole ...

The genomic landscape of high hyperdiploid childhood acute ...

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia. Leukemia 26, 1797-1803. (2012). 25 ...

Upfront Treatment Influences the Composition of Genetic Alterations ...

Genomic alterations in relapsed B-cell precursor acute lymphoblastic leukemia (BCP-ALL) may provide.

Abstract IA23: The genomic landscape of acute lymphoblastic ...

Several genetic alterations are associated with an increased risk of leukemia relapse, including IKZF1, CREBBP, and NT5C2. Moreover, studies ...

The genomic landscape of high hyperdiploid childhood acute ...

High hyperdiploid (51-67 chromosomes) acute lymphoblastic leukemia (ALL) is one of the most common childhood malignancies, comprising 30% of all pediatric B ...

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Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. Relevance, Medical. Data types, Whole genome sequencing

The genomic landscape of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of ...

The evolution of relapse of adult T cell acute lymphoblastic leukemia

Our results show that in the 19 cases the relapse is driven by genetic mutations, and that resistant cells appear in the population of blasts several months ...

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To study the mechanisms of relapse in acute lymphoblastic leukemia (ALL), we performed whole-genome sequencing of 103 diagnosis-relapse-germline trios and ...