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Insights into Protein–DNA Interactions through Structure Network ...


Insights into DNA Solvation Found in Protein-DNA Structures

The proteins that bind double-helical DNA present various microenvironments that sense and/or induce signals in the genetic material.

DNA-Protein Interaction Analysis - Illumina

Analysis of DNA-protein interactions provides researchers with insight into regulation events that are critical for many biological processes and disease ...

Artificial Intelligence Reveals Protein-DNA Interactions - SynBioBeta

Protein structure prediction has improved significantly in recent years, but predicting their interactions with DNA will be key to realizing ...

Structure-based prediction of protein-nucleic acid binding using ...

Structural models of proteins bound to nucleic acids (NA) provide insights into the chemical, electrostatic, and geometric properties of the ...

(IUCr) Structure solution of DNA-binding proteins and complexes ...

The molecular detail of protein–DNA interactions can be best visualized through crystallography, and structures emphasizing insight into the principles of ...

Molecular insights into the prototypical single-stranded DNA-binding ...

... network of SSB-protein interactions reveals many common elements across the different interactions. ... structures reveals insight into stalled DNA ...

network analysis of molecular dynamics data and protein–nucleic ...

Abstract Network theory is now a method of choice to gain insights in understanding protein structure, folding and function. In combination with molecular ...

NAPS update: network analysis of molecular dynamics data and ...

Network theory is now a method of choice to gain insights in understanding protein structure, folding and function. ... Updated version of NAPS now facilitates ...

Protein–DNA/RNA Interactions: An Overview of Investigation ...

These interactions affect fundamental processes such as replication, transcription, and repair in the case of DNA, as well as transport, ...

Accurate prediction of protein–nucleic acid complexes using ...

Protein–RNA and protein–DNA complexes play critical roles in biology. Despite considerable recent advances in protein structure prediction, ...

Physicochemical models of protein–DNA binding with ... - PNAS

Structural information from TF–DNA complexes provides insight into specific mechanisms used by a TF to recognize DNA targets (2–5). One example ...

Advances in the Application of Protein Language Modeling ... - MDPI

It achieves this by aggregating binding residues across multiple similar or identical protein complexes, where proteins may interact with different DNA or RNA ...

Structural insights into DNA recognition by the BEN domain of the ...

Consistent with these in vivo observations, we identified an optimal DNA-binding sequence of AAATCTCG by protein binding microarray, which was ...

1CJG: NMR STRUCTURE OF LAC REPRESSOR HP62-DNA ...

The protein-protein and protein-DNA interactions involving the hinge region and the deformations in the DNA structure could be delineated in atomic detail.

Using a structural and logics systems approach to infer bHLH–DNA ...

... structures to gain insight into the molecular mechanisms of protein–DNA interactions. ... networks by protein-DNA and protein-protein interaction.

Introduction to Protein-DNA Interactions: Structure, Thermodynamics ...

A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create a unified view of the ...

Insights on protein–DNA recognition by coarse grain modelling

groups within the DNA grooves in the protein–DNA interactions. Second, we ... Comparable results were obtained when using deformed protein structures and native ...

Insights into the quaternary association of proteins through structure ...

For example, the complete protein interaction network, or the regulatory ... and protein–DNA interactions [44]. The interface analysis of a set of ...

an accurate method for predicting DNA-binding sites on protein ...

Zhou, Prediction of protein interaction sites from sequence profile and residue neighbor list, Proteins, № 44, с. · Chen, Prediction of interface residues in ...

Bridging protein local structures and protein functions | Amino Acids

In particular, we emphasize the newly developed structure-based methods, which are able to identify locally structural motifs and reveal their ...