Micronuclei|based model system reveals functional consequences ...

Chromosome length and gene density contribute to micronuclear ...

... effects on micronuclei lamina structure, rupture timing, and cellular outcomes. ... based model system reveals functional consequences of.

Linking Micronuclei to Chromosome Fragmentation | Request PDF

Additionally, the formation of micronuclei may cause chromatin breakage and clustered chromosomal rearrangements, a phenomenon known as "chromothripsis" (124) ( ...

A role for Nup153 in nuclear assembly reveals differential ...

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells. Elife 8, e50292. Crossref, Medline, Google ...

Image-based identification and isolation of micronucleated cells to ...

Recent advances in isolating cells based on visual phenotypes have transformed our ability to identify the mechanisms and consequences of complex traits.

Zuzana Storchová - Fachbereich Biologie an der RPTU

... Systems approaches identify the consequences of ... Micronuclei-based model system reveals functional consequences of chromothripsis in human cells.

the causes and consequences of micronucleus rupture

[학술지] Kneissig, M / 2019 / Micronuclei-based model system reveals functional consequences of chromothripsis in human cells / Elife / 8 : e50292; 50 ...

An image analysis approach to characterize micronuclei differences ...

Kneissig, Micronuclei-based model system reveals functional consequences of chromothripsis in human cells, eLife, № 8 https://doi.org/10.7554/eLife.50292; Ye ...

Planetary boundaries - Stockholm Resilience Centre

Advances the understanding of complex social-ecological systems with new insights into ecosystem management practices and long-term sustainability.

SAMHSA's Concept of Trauma and Guidance for a Trauma-Informed ...

justice system reveal high rates of mental and substance use disorders and ... model of posttraumatic stress disorder and physical health outcomes.

DNA language models are powerful predictors of genome-wide ...

We propose a genome-wide variant effect prediction approach based on unsupervised DNA language models, achieving state-of-the-art performance in Arabidopsis ...

Digital Twin Technology & GIS | What is a Digital Twin? - Esri

... system (GIS) technology. Time aware. GIS-based digital twins go beyond 3D models as they reflect change over time—showing historic, current, and future states.

Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei

MN have reduced functioning compared to primary nuclei in the same cell, although the two compartments appear to be structurally comparable. Here we show that ...

What Matters to Student Success: A Review of the Literature

toward competency-based models; introducing more choice and competition in the system where high ... (2000) college impact model, Titus ...

Earth beyond six of nine planetary boundaries | Science Advances

Last, the importance of considering human impacts on components of the global environment in a system context is illustrated using a modeling ...

Questions and Answers about CRISPR | Broad Institute

With these systems, researchers can permanently modify genes in living cells and organisms and, in the future, may make it possible to correct mutations at ...

The circular economy in detail - Ellen MacArthur Foundation

A circular economy reveals and designs out the negative impacts of economic activity that cause damage to human health and natural systems. This ...

Google DeepMind and Isomorphic Labs introduce AlphaFold 3 AI ...

Introducing AlphaFold 3, a new AI model developed by Google DeepMind and Isomorphic Labs. ... system to surpass physics-based tools for ...

Skills-based organizations | Deloitte Insights

Organizations are moving toward a whole new operating model for work and the workforce that places skills, more than jobs, at the center.

Chapter 12: DNA Damage and Repair - Chemistry

The next section will highlight common types of DNA damage and their effects. If a DNA polymerase encounters a damaged DNA base in the template DNA during ...

Potential health effects of exposure to electromagnetic fields (EMF)

effects on the nervous system function or on disease processes in the nervous system. ... at 0.5 mT using a solenoid-based exposure system for 30 days beginning ...