Pluripotent stem cell energy metabolism

Energy metabolism in human pluripotent stem cells and their ...

Energy metabolism in human pluripotent stem cells and their differentiated counterparts ... Varum, S and Rodrigues, AS and Moura, MB and ...

Measuring energy metabolism in cultured cells, including human ...

56 References · UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells · The biology of cancer: metabolic reprogramming ...

Measuring energy metabolism in cultured cells, including human ...

Measurements of glycolysis and mitochondrial function are required to quantify energy metabolism in a wide variety of cellular contexts.

Energy Metabolism in Human Pluripotent Stem and Differentiated ...

We used fibroblasts, human induced PSCs, and human embryonic stem cells to monitor changes in basal metabolic levels according to cell number ...

Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell ...

However, induced pluripotent stem cells (iPSC) retain transcriptional memory, epigenetic memory, and metabolic memory from their somatic cells ...

Metabolism in pluripotency: Both driver and passenger?

Cell Stem Cell 21,. 502–516.e9 CrossRef Medline. 54. Teslaa, T., and Teitell, M. A. (2014) Pluripotent stem cell energy metabo- lism: an ...

15 - The metabolic framework of pluripotent stem cells and potential ...

This chapter focuses on the metabolic framework that sustains pluripotent stem cells in culture, potential mechanisms that regulate the physiology of these ...

Metabolism in Human Pluripotent Stem Cells and Cardiomyocytes ...

Downstream of such transcriptional regulatory networks, various stem cell-specific metabolic programs are used to produce energy and metabolites as necessary.

The metabolome of induced pluripotent stem cells reveals metabolic ...

Metabolism is vital to every aspect of cell function, yet the metabolome of induced pluripotent stem cells (iPSCs) remains largely ...

The metabolic programming of stem cells - Genes Dev

Metabolic switches linked to pluripotency and embryonic stem cell ... Energy metabolism in human pluripotent stem cells and their differ- entiated counterparts.

from embryonic development to stem cell differentiation - Browse ...

Transitions through pluripotent stem cell states, differentiation, and reprogramming, involve substantial metabolic remodeling. These metabolic ...

A roadmap for the characterization of energy metabolism in human ...

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are an increasingly employed model in cardiac research and drug discovery.

Energy Metabolism in Human Pluripotent Stem Cells and Their ...

Human embryonic stem cells (hESCs) are self-renewing and pluripotent cells derived from the inner cell mass (ICM) of a blastocyst prior to ...

Metabolic remodeling during somatic cell reprogramming to induced ...

Compared with their somatic counterparts, pluripotent stem cells, including embryonic stem cells and iPSCs, exhibit a high rate of glycolysis ...

Mitochondrial energy metabolic transcriptome profiles during ...

The concomitant development of myofibrils and mitochondria is a major process in cardiac differentiation from pluripotent stem cells (PSCs) [1].

Manipulation of Pluripotent Stem Cell Metabolism for Clinical ...

Pluripotent stem cells (PSCs) have the capacity to differentiate into various types of cells, and are promising cell sources for ...

Metabolic control of primed human pluripotent stem cell fate and ...

Abstract: A hallmark of cancer cells is the metabolic switch from oxidative phosphorylation (OXPHOS) to glycolysis, a phenomenon referred to as the 'Warburg ...

A roadmap for the characterization of energy metabolism in human ...

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are an increasingly employed model in cardiac research and drug ...

Distinct requirements for energy metabolism in mouse primordial ...

Our findings in this study demonstrate not only distinct energy metabolisms in PGCs and pluripotent stem cells (PSCs), but also the essential contribution of ...

Metabolic Regulation of Cardiac Differentiation and Maturation in ...

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are expected to be useful for ...